… To study the effect of DNA methylation on eukaryotic genes, we previously developed a
convenient method for methylating all CpG residues in vitro (8, 14). To this end, gene sequences …

… DNA METHYLATION AND DEVELOPMENT Although it is … in tissue culture that DNA methylation
inhibits gene expression, it is … Temporal and regional changes in DNA methylation in the …

… in tumorigenesis is the silencing of gene transcription associated with gains of DNA
methylation in normally unmethylated gene promoter regions (1,2). Delineation of the specific …

… between DNAm and gene expression has remained unclear … paired DNA methylation and
gene expression data. Given … different brain regions, we chose to study four regions from each …

… methylation. Using mostly myogenesis as an example, we describe new insights into DNA
methylation‘s role in controlling gene expression in … in this region (Figure 1B) . In summary, the …

… on DNA methylation and gene expressions in cancer. Then we provide analysis of DNA
methylation and gene expression … DNA methylation in various genomic regions and expression …

… of DNA methylation on gene expression has linked methylation of CpG sites in the gene
promoter region with the decrease in gene expression. … this traditional role of DNA methylation. …

… Here we show that total DNA methylation of the human y-globin gene region prevents
globin transcription in L-cells (Figure 2). We have reached the same conclusion in a similar …

… We also observe that regions … HOX gene expression [34] and DNA methylation [35], we
show inter-individual variation and correlation between DNA methylation and gene expression in …

… We examined the regional distribution of methylation sites (n=517) that are associated with
… We measured gene expression and DNA methylation from the same blood sample so that …