[HTML][HTML] NRF2, a transcription factor for stress response and beyond

F He, X Ru, T Wen - International journal of molecular sciences, 2020 - mdpi.com
NRF2 lies at the center of a complex regulatory network and establishes NRF2 as a truly
pleiotropic transcription factor… Here we summarize the complex regulatory network of NRF2

Transcriptional regulation by Nrf2

C Tonelli, IIC Chio, DA Tuveson - Antioxidants & redox signaling, 2018 - liebertpub.com
… Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that … Understanding the
regulation of Nrf2 activity and … Recent Advances: Nrf2 regulates the transcription of components of …

Oncogenic functions of the transcription factor Nrf2

I Gañán-Gómez, Y Wei, H Yang… - Free Radical Biology …, 2013 - Elsevier
… from reactive oxygen species, Nrf2 seems to play a direct … , Nrf2 activity is connected with
oncogenic kinase pathways, structural proteins, hormonal regulation, other transcription factors, …

[HTML][HTML] Regulation of Nrf2 signaling

R Li, Z Jia, H Zhu - Reactive oxygen species (Apex, NC), 2019 - ncbi.nlm.nih.gov
… the CNC subfamily of transcription factors include nuclear factor E2-related factors 1 and 3
(… efficacy of enzyme inducers is lost in Nrf2 transcription factor-deficient mice. Proc Natl Acad …

[HTML][HTML] Regulation of γ-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2

AC Wild, HR Moinova, RT Mulcahy - Journal of Biological Chemistry, 1999 - ASBMB
… elements (T-MARE) and the NF-E2-binding sites, suggesting that transcription factors
recognizing these sequences may bind to and regulate expression through EpRE sequences ( …

Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes

M Pajares, N Jiménez-Moreno, ÁJ García-Yagüe… - Autophagy, 2016 - Taylor & Francis
… autophagy genes is connected through additional common regulatory transcription factor(s). …
is regulated by NFE2L2/NRF2 (nuclear factor, erythroid 2 like 2). The transcription factor

Regulation of Nrf2—an update

SK Niture, R Khatri, AK Jaiswal - Free Radical Biology and Medicine, 2014 - Elsevier
Nrf2 is a leucine zipper/CNC protein that, when present in the nucleus, functions as a
transcription factor that regulates the coordinated activation of a battery of cytoprotective genes that …

Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2

A You, C Nam, N Wakabayashi, M Yamamoto… - Archives of biochemistry …, 2011 - Elsevier
Nrf2 is a member of the CNC-bZIP (cap’n’collar family of basic leucine-zipper) transcription
factors and its activity is mainly regulated … protein for ubiquitinylation of Nrf2, and controls a …

Regulatory crosstalk between the oxidative stress-related transcription factor Nfe2l2/Nrf2 and mitochondria

I Ryoo, MK Kwak - Toxicology and applied pharmacology, 2018 - Elsevier
Nrf2 contributes to mitochondrial regulation through more divergent intermolecular linkages.
Nrf2 … the direct upregulation of mitochondrial transcription factors and is involved in the …

[HTML][HTML] Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

M Pajares, A Cuadrado, AI Rojo - Redox biology, 2017 - Elsevier
transcriptional modulation of proteostasis exerted by the transcription factor NRF2 (nuclear
factor (… Indeed, different kinases have been shown to phosphorylate and regulate NRF2. For …