Molecular regulation of cardiac hypertrophy

SP Barry, SM Davidson, PA Townsend - The international journal of …, 2008 - Elsevier
… and cellular models of cardiac hypertrophy suggests that pathological hypertrophy can be …
of hypertrophy. In this review we describe the molecular characteristics of cardiac hypertrophy

Regulation of cardiac hypertrophy by intracellular signalling pathways

J Heineke, JD Molkentin - Nature reviews Molecular cell biology, 2006 - nature.com
regulated shuttling of class II histone deacetylases (HDACs) have been shown to regulate
cardiac hypertrophy… shed light on the signalling networks that mediate cardiac hypertrophy. …

Immune cell and other noncardiomyocyte regulation of cardiac hypertrophy and remodeling

RA Frieler, RM Mortensen - Circulation, 2015 - Am Heart Assoc
… fibrosis without affecting hypertrophy or cardiac function. … reduced hypertrophy and
fibrosis and prevented cardiac … is known to induce cardiac hypertrophy; therefore, the TGF-β…

[HTML][HTML] Protein kinase cascades in the regulation of cardiac hypertrophy

GW Dorn, T Force - The Journal of clinical investigation, 2005 - Am Soc Clin Investig
cardiac hypertrophy: normal growth, growth induced by physical conditioning (ie, physiologic
hypertrophy)… normal and exercise-induced cardiac growth are regulated in large part by the …

Mechanisms of physiological and pathological cardiac hypertrophy

M Nakamura, J Sadoshima - Nature Reviews Cardiology, 2018 - nature.com
… , positively or negatively regulate cardiac hypertrophy. In this Review, … hypertrophy, with a
particular emphasis on the role of metabolic remodelling in both forms of cardiac hypertrophy, …

Physiological and pathological cardiac hypertrophy

I Shimizu, T Minamino - Journal of molecular and cellular cardiology, 2016 - Elsevier
… in maintenance of cardiac homeostasis. Cardiac hypertrophy is classified as physiological
when it is associated with normal cardiac function or as pathological when associated with …

[HTML][HTML] Redox regulation of cardiac hypertrophy

CM Sag, CXC Santos, AM Shah - Journal of molecular and cellular …, 2014 - Elsevier
cardiac hypertrophy. Indeed, these redox modifications may be intricately linked with the
process of hypertrophy … pathways and their roles in cardiac hypertrophy. This article is part of a …

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response

KR Chien, KU Knowlton, S Chien - The FASEB Journal, 1991 - Wiley Online Library
regulate cardiac genes during growth and hypertrophy. One of the first detectable changes
in cardiac … expression, which is distinct for the hypertrophic response, and is conserved in …

Calcium–calcineurin signaling in the regulation of cardiac hypertrophy

BJ Wilkins, JD Molkentin - Biochemical and biophysical research …, 2004 - Elsevier
Cardiac hypertrophy is a leading predicator of progressive heart disease that often leads to
heart failure and a loss of cardiac … pathways that regulate cardiac myocyte hypertrophy, as …

Molecular targets and regulators of cardiac hypertrophy

A Rohini, N Agrawal, CN Koyani, R Singh - Pharmacological research, 2010 - Elsevier
… signaling, etc. are known to regulate heart. By using genetic and cellular models of cardiac
hypertrophy it has been proved that pathological hypertrophy can be prevented or reversed. …