Role of the B1 Kinin Receptor in the Regulation of Cardiac Function and Remodeling After Myocardial Infarction
… lack of B 1 worsens cardiac remodeling after MI. … cardiac remodeling after MI. In the present
study, we further showed that targeted deletion of B 1 receptors did not aggravate remodeling …
study, we further showed that targeted deletion of B 1 receptors did not aggravate remodeling …
The inflammasome in myocardial injury and cardiac remodeling
… promotes adverse cardiac remodeling and failure. Future Directions: Pilot clinical trials have
explored blockade of the inflammasome-derived IL-1β and have shown beneficial effects on …
explored blockade of the inflammasome-derived IL-1β and have shown beneficial effects on …
Elucidating the molecular mechanism of cardiac remodeling using a comparative genomic approach
M Mirotsou, CMH Watanabe… - Physiological …, 2003 - journals.physiology.org
… murine models of cardiac hypertrophy and remodeling: myocardial … of cardiac remodeling.
This comparison might provide useful insights in the understanding of cardiac remodeling with …
This comparison might provide useful insights in the understanding of cardiac remodeling with …
Autocrine signaling in cardiac remodeling: a rich source of therapeutic targets
VFM Segers, GW De Keulenaer - Journal of the American Heart …, 2021 - Am Heart Assoc
… and prostate epithelial development, 16 , 17 cardiac development, 18 tissue response to
injury, 19 and, as will be discussed in this review, cardiac remodeling and heart failure. …
injury, 19 and, as will be discussed in this review, cardiac remodeling and heart failure. …
Mep1a contributes to Ang II-induced cardiac remodeling by promoting cardiac hypertrophy, fibrosis and inflammation
W Ge, C Hou, W Zhang, X Guo, P Gao, X Song… - Journal of molecular and …, 2021 - Elsevier
… to cardiac remodeling. In light of our findings that blocking Mep1a can ameliorate cardiac
remodeling via inhibition of cardiac … for therapeutic targeting to prevent cardiac remodeling. …
remodeling via inhibition of cardiac … for therapeutic targeting to prevent cardiac remodeling. …
Interferon regulatory factor 1 is required for cardiac remodeling in response to pressure overload
DS Jiang, L Li, L Huang, J Gong, H Xia, X Liu… - …, 2014 - Am Heart Assoc
… To further define the effects of IRF1 deficiency on maladaptive cardiac remodeling, we
evaluated fibrosis that is a classical feature of pathological cardiac hypertrophy. Paraffin-…
evaluated fibrosis that is a classical feature of pathological cardiac hypertrophy. Paraffin-…
Monocyte and macrophage contributions to cardiac remodeling
… strategies, which can modulate adverse cardiac remodeling and prevent heart failure. … and
macrophages, to the pathogenesis of cardiac remodeling with a focus on the fibrotic response…
macrophages, to the pathogenesis of cardiac remodeling with a focus on the fibrotic response…
[HTML][HTML] Significance of the transcription factor KLF5 in cardiovascular remodeling
R Nagai, T Suzuki, K Aizawa, T Shindo… - Journal of Thrombosis and …, 2005 - Elsevier
… in cardiovascular remodeling and a potential therapeutic target for cardiovascular disease.
… KLF5 in cardiovascular remodeling and regulation of transcriptional activities of KLF5 [11]. …
… KLF5 in cardiovascular remodeling and regulation of transcriptional activities of KLF5 [11]. …
Alterations in G protein and MAP kinase signaling pathways during cardiac remodeling in hypertension and heart failure
… factors and gene expression related to cardiac growth. To determine the profile of MAP
kinase alterations involved in cardiac remodeling, we used semiquantitative immunoblotting for …
kinase alterations involved in cardiac remodeling, we used semiquantitative immunoblotting for …
Mapping cardiac remodeling in chronic kidney disease
… cardiac death and recurrent heart failure. The mechanisms of cardiac remodeling are largely
unclear… To dissect molecular and cellular mechanisms of cardiac remodeling in CKD in an …
unclear… To dissect molecular and cellular mechanisms of cardiac remodeling in CKD in an …