… and this can be achieved by regulating inflammasome activity. However, we have, as yet,
little understanding of the mechanisms of this regulation. In particular the negative feedbacks, …

… Therefore, activation of the inflammasome must be finely controlled to avoid overt tissue
damage. These regulatory activities are governed by scaffolding proteins and post-translational …

… Here we discuss the various regulatory mechanisms that have evolved to keep inflammasome
… Failure to curb the activity of inflammasomes is exemplified by the finding that deregulated …

… regulates HSPC production through inflammasome activity in the zebrafish embryo. Furthermore,
we demonstrate the conservation of inflammasome activation in modulating expansion …

… not surprising that dysregulated inflammasome activity is associated with … regulation of
inflammasome activity and therapeutic interventions targeting structures related to inflammasome …

… inflammasome nucleation. As NLRP3 tyrosine modification by BTK also positively regulates
IL-1β release, we propose BTK as a multifunctional positive regulator of NLRP3 regulation …

… via the regulation of the NF-κB activation pathway. Lys-63-specific deubiquitinase BRCC36
(BRCC3) and IL-1 receptor-associated kinase 1 (IRAK1) regulate NLRP3 inflammasome …

… Therefore, precise regulation of inflammasome activities is critical for adequate immune
protection while limiting collateral tissue damage. In this review, we focus on the emerging roles …

… of inflammasomes is unclear. Here, we show that the DUBs USP7 and USP47 regulate
inflammasome … and USP47 are regulated at the activity level by inflammasome‐activating signals …

… As such, their activity is tightly regulated at the transcriptional and … inflammasomes and
transcription regulation, we will focus on the transcriptional regulation of specific inflammasome …