The inhibitory effects of quercetin on obesity and obesity-induced inflammation by regulation of MAPK signaling

MJ Seo, YJ Lee, JH Hwang, KJ Kim, BY Lee - The Journal of Nutritional …, 2015 - Elsevier
… Research has suggested that obesity is linked to … of quercetin on lipid accumulation and
obesity-induced inflammation using 3T3-L1, RAW264.7, zebrafish and mouse models. Quercetin

The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways

J Ahn, H Lee, S Kim, J Park, T Ha - Biochemical and biophysical research …, 2008 - Elsevier
… events involved in quercetin regulation of obesity has become … mechanisms by which
quercetin inhibits adipogenesis and … quercetin attenuates adipogenesis through the up-regulation

Therapeutic effects of quercetin on inflammation, obesity, and type 2 diabetes

S Chen, H Jiang, X Wu, J Fang - Mediators of inflammation, 2016 - Wiley Online Library
… is that quercetin works to block adipogenesis actions through stimulating the MAPK signal
… Other authors have shown a role for quercetin in the regulation of hepatic gene expression …

Quercetin protects against obesity‐induced skeletal muscle inflammation and atrophy

NH Le, CS Kim, T Park, JHY Park… - Mediators of …, 2014 - Wiley Online Library
… ‐fed obese mice, and protected against the reduction of muscle mass and muscle fiber size.
In vitro, quercetin … of their signaling molecules (ERK, p38 MAPK, and NF‐κB) in cocultured …

Modulation of chronic inflammation by quercetin: The beneficial effects on obesity

S Sato, Y Mukai - Journal of inflammation research, 2020 - Taylor & Francis
… the activation of TLR4-mediated NF-κB and MAPK signaling pathways. Citation46 Therefore,
… Citation106 Therefore, quercetin may epigenetically regulate the obesity and inflammation. …

Quercetin Regulates Lipid Metabolism and Fat Accumulation by Regulating Inflammatory Responses and Glycometabolism Pathways: A Review

Y Wang, Z Li, J He, Y Zhao - Nutrients, 2024 - mdpi.com
… -regulated after utilizing quercetin in vitro tests and obese mice models. Further investigation
found that quercetin … Besides, due to its effect on MAPK signaling pathways, quercetin can …

[HTML][HTML] Combination treatment with quercetin and resveratrol attenuates high fat diet‑induced obesity and associated inflammation in rats via the AMPKα1/SIRT1 …

L Zhao, F Cen, F Tian, MJ Li… - Experimental and …, 2017 - spandidos-publications.com
Quercetin is a polyphenolic flavonoid compound present in a variety of fruits and vegetables…
that quercetin exerts anti-obesity activity via the mitogen-activated protein kinase (MAPK) …

Role of quercetin as an alternative for obesity treatment: you are what you eat!

SF Nabavi, GL Russo, M Daglia, SM Nabavi - Food chemistry, 2015 - Elsevier
obesity through the regulation of different molecular pathways, such as mitogen-activated
protein kinase (MAPK), … -activated receptor-α and sterol regulatory element-binding protein-1c …

Quercetin attenuates adipose hypertrophy, in part through activation of adipogenesis in rats fed a high-fat diet

DJ Perdicaro, CR Lanzi, JG Tudela, RM Miatello… - The Journal of …, 2020 - Elsevier
Obesity is one of the main public health concerns worldwide [… adipogenic regulators that
positively control each other and … Among flavonoids, the flavonol quercetin (Q) is one of the …

Quercetin suppresses inflammation by reducing ERK1/2 phosphorylation and NF kappa B activation in leptin-induced human umbilical vein endothelial cells …

MR Indra, S Karyono, R Ratnawati, SG Malik - BMC research notes, 2013 - Springer
… in obesity have been reported to trigger endothelial dysfunction. The objective of this study
was to elucidate the role of quercetin … that 125 μM quercetin was able to down-regulate Ob-Ra …