Regulation of pathogenesis and immunity in helminth infections

RM Maizels, EJ Pearce, D Artis… - Journal of Experimental …, 2009 - rupress.org
… about the biology of helminth infections and how mammalian … and regulation that controls
the outcome of helminth infections. … regulatory pathways that are induced by helminth infections

Helminth infections and host immune regulation

HJ McSorley, RM Maizels - Clinical microbiology reviews, 2012 - Am Soc Microbiol
… However, these potentially pathogenic responses also have to be regulated by the host
immune system through counterbalancing immunoregulatory mechanisms. Moreover, it is now …

T cells in helminth infection: the regulators and the regulated

MD Taylor, N van der Werf, RM Maizels - Trends in immunology, 2012 - cell.com
… immunity in dampening potentially pathogenic inflammatory responses and Foxp3 + …
helminth infections. For example, expanded and activated Foxp3 + Treg populations down-regulate

[HTML][HTML] Helminth parasites and immune regulation

PH Gazzinelli-Guimaraes, TB Nutman - F1000Research, 2018 - ncbi.nlm.nih.gov
Helminth-induced immunoregulation occurs through the induction of regulatory T cells or
Th2-… in understanding the immune responses to helminth infection, emphasizing the strategies/…

Immune regulation by helminth parasites: cellular and molecular mechanisms

RM Maizels, M Yazdanbakhsh - Nature Reviews Immunology, 2003 - nature.com
… protects the host not from infection per se, but from the potential pathogenic damage caused
by … 4: The regulatory environment that we propose might develop during helminth infection. …

Macrophage regulation & function in helminth infection

A Lechner, S Bohnacker, J Esser-von Bieren - Seminars in immunology, 2021 - Elsevier
… or increased susceptibility to infections or cancer. However, the … regulation during helminth
infection have only partially been defined. In particular, long-term effects of helminth infection

[HTML][HTML] Regulation of the host immune system by helminth parasites

RM Maizels, HJ McSorley - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
… However, helminth infection can also be detrimental in reducing vaccine responses, …
removes the need to introduce a potentially pathogenic parasite in the treatment of disease. …

Helminth parasites–masters of regulation

RM Maizels, A Balic, N Gomez‐Escobar… - Immunological …, 2004 - Wiley Online Library
… normally considered as ‘pathogenic’ for considerable time … of responsiveness is occurring
in helminth infection. Perhaps both … for regulatory T-cell activity in human helminth infection but …

Regulation of allergy and autoimmunity in helminth infection

MS Wilson, RM Maizels - Clinical reviews in allergy & immunology, 2004 - Springer
… by helminths, and we discuss the likely mechanisms by which helminths could be establishing
a strongly regulatory … Understanding and harnessing the modulatory capacity of helminths

Induction of regulatory cells by helminth parasites: exploitation for the treatment of inflammatory diseases

CM Finlay, KP Walsh, KHG Mills - Immunological reviews, 2014 - Wiley Online Library
… against pathogenic T cells that mediate allergy and autoimmunity and how … , it was
suggested that regulatory immune responses induced by helminth infection inhibited Th2-driven …