… Diminished hypoxic ventilatory drive has been attributed to a genetic predisposition in a …
reduced hypoxic ventilatory response gave a history of symptoms suggesting sleep apnea for 20 …

… Ventilatory instability may play an important role in the pathogenesis of obstructive sleep
apnea. We hypothesized that the influence of ventilatory instability in this disorder would vary …

… apnea (OSA), we hypothesized that OSA patients have an underlying instability of … ventilation.
Our finding of a difference in dynamic ventilatory control of obese OSA patients and control …

… the breathing phase after both obstructive and mixed apnea episodes but did not do so after
central apneic … induced by apneas and the breathing parameters (f, VT, VE) in the following …

… chemical control of respiration during sleep in … ventilatory stability during sleep (6, 7). It takes
advantage of the ability of proportional assist ventilation (PAV) (8) to augment the ventilatory …

… on the apnea–hypopnea index (AHI) in six obstructive sleep apnea patients with a relatively
high loop gain (LG) and six with a low LG. LG is a measure of ventilatory control stability. In …

… with obstructive sleep apnea who did not retain carbon dioxide while awake. Our data …
that abnormalities in the control of breathing exist in patients with obstructive sleep apnea. …

… They further expanded on our understanding of ventilatory control and periodic breathing
with the development mathematical models that featured chemosensitivity as a predictor of …

… Elevated loop gain, consequent to hypersensitive ventilatory control, is a primary nonanatomical
cause of obstructive sleep apnoea (OSA) but it is not possible to quantify this in the clinic…

… Finally, using an iron-lung model of passive ventilation, data from our laboratory have
demonstrated that during inspiration, there is an extremely tight correlation between epiglottic …