… regulatory T cell subsets in the peripheral blood of patients with SLE. However, the suppressive
function of CD4+CD25+ cells is defective in a significant proportion of these patients. It …

… T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory
T cells … of CD4 + CD25 + regulatory T cells in immune system impairment in patients with …

… controls and patients during … T R number and reduced IL-12 mononuclear cell production
(r=0.362, P=0.05). This work demonstrates that CD4 + CD25 + T cells are decreased in patients …

OBJECTIVE—Regulatory T-cells (Tregs) have catalyzed the field of immune regulation.
However, translating Treg-based therapies from animal models of autoimmunity to human …

… Multiple sclerosis (MS) is an inflammatory disease thought to be mediated by T cells … hi
regulatory T cells play a role in the breakdown of immunologic self-tolerance in patients with MS. …

… This translational study reports on the phenotypic and functional properties of regulatory
T cells (Treg) in patients with acute myelogenous leukemia (AML) at diagnosis and following …

… Current evidence indicates that regulatory T cells (Tregs) actively suppress autoreactive …
Our results suggest that patients with SLE have a lower percentage of CD4CD25bright T cells, …

… −/low/high subpopulations in RCC patients The phenotype of regulatory T cells has been
well … RCC patients and healthy donors. The rationale for this being that an excess of activated …

Background Regulatory T cells (Tregs) have important functions in peripheral immune
tolerance. Dysfunction of Tregs is considered to be a pivotal cause of autoimmune diseases, …

… Naturally occurring CD4 + CD25 + regulatory T cells (Tregs) are a subpopulation of lymphocytes
that are capable of suppressing the progression of experimental autoimmune disorders. …