… CD4 + CD25 + regulatory T cells (Tregs) exhibit regulatory/… and effector function of autoreactive
T cells that have escaped … cell (APC) function or suppression of responding T cells [16]. …

Objectives Recent data debate the suitability of Helios, an Ikaros family member, as a marker
for thymic-derived regulatory T cells (Treg). Nevertheless, Foxp3 + Helios + Treg may be of …

… Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody
… Regulatory T cells (Treg) play critical roles in the induction of peripheral tolerance to self- …

… lupus T cells to get activated [6]. Additionally, the failure of the regulatory CD4+ and CD8+ T
lymphocytes … the normal physiology of T cells are disturbed and why regulatory T cells fail to …

… Fluorescence-activated cell sorting analysis of peripheral regulatory T cell (Treg) … from
patients with cutaneous lupus erythematosus (CLE). Peripheral blood mononuclear cells (PBMCs) …

… H )17 cell production with down-regulation of the T H 1 and regulatory T cell (T reg ) cytokines,
IFNγ and TGFβ, and the up-regulation of IL-6 and IL-17, T H17 cytokines [22]. Additionally, …

… Thus, the therapeutic effects of antagonizing Th17 cells for the treatment of SLE in the clinic
… of effector T cells is always closely related to the depletion and dysfunction of Treg cells. …

… + T cells in 43 patients with systemic lupus erythematosus (SLE). … in CD4+CD25+ and
CD4+CD25high T cells numbers in patients … Coexpression of FoxP3 on CD4+CD25+ T cells was …

… Systemic Lupus Erythematosus (SLE) is a chronic, systemic … Regulatory T cells (T REG ) are
those CD4+ T cells that … + (T REG ) cells and the Mean Fluorescence Index (MFI) of T REG in …

… searched using ‘systemic lupus erythematosus’ and ‘regulatory T-cells’ as relevant key …
among peripheral blood mononuclear cells (PBMCs) and CD4 + T-cells was performed using …