[HTML][HTML] Disturbed T cell signaling and altered Th17 and regulatory T cell subsets in the pathogenesis of systemic lupus erythematosus

N Rother, J van der Vlag - Frontiers in immunology, 2015 - frontiersin.org
… depends on autoreactive T cells. In this … of T cell signaling, and Th17 and regulatory T cells
(Tregs) in the development of SLE. T cell receptor (TCR) signaling appears to be aberrant in T

Dysfunctional CD4+, CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon‐α–producing antigen‐presenting cells

B Yan, S Ye, G Chen, M Kuang… - Arthritis & Rheumatism …, 2008 - Wiley Online Library
… by CD4+,CD25+ regulatory T cells, which constitute 5–10% of peripheral blood CD4+ T cells
in normal mice and humans (1, 2). Systemic lupus erythematosus (SLE) is an autoimmune …

[HTML][HTML] The regulatory T cell in active systemic lupus erythematosus patients: a systemic review and meta-analysis

W Li, C Deng, H Yang, G Wang - Frontiers in immunology, 2019 - frontiersin.org
… ,” combined with “systemic lupus erythematosus.” Reviews were excluded and only articles
lupus erythematosus exhibits a dynamic and continuum spectrum of effector/regulatory T cells

Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis

…, E Lazaro, L Couzi, P Duffau, T Barnetche… - Science Translational …, 2021 - science.org
… P-selectin as a treatment for lupus Dysfunctional regulatory T (T reg ) cells are known to be
… pathogenesis of systemic lupus erythematosus (SLE), but the mechanisms mediating T reg …

Quantification of regulatory T cells in peripheral blood of patients with systemic lupus erythematosus

M Habibagahi, Z Habibagahi, M Jaberipour… - Rheumatology …, 2011 - Springer
… disease states to better elucidate the role of regulatory T cells in the course of the disease. …
of regulatory T cells in patients with both active and inactive SLE disease by considering cells

[HTML][HTML] New insights in systemic lupus erythematosus: from regulatory T cells to CAR-T-cell strategies

M Doglio, T Alexander, N Del Papa… - Journal of Allergy and …, 2022 - Elsevier
… less toxicity than autologous hematopoietic stem cell transplantation. An emerging field is to
… of regulatory T cells, which are dysfunctional in patients with systemic lupus erythematous, …

[HTML][HTML] Increased CD45RA+FoxP3low Regulatory T Cells with Impaired Suppressive Function in Patients with Systemic Lupus Erythematosus

X Pan, X Yuan, Y Zheng, W Wang, J Shan, F Lin… - PloS one, 2012 - journals.plos.org
… Human regulatory T cells (Treg cells) play an important role in T cell homeostasis and are
critical regulators of … Quantitative and/or qualitative deficiencies in Treg cells could lead to the …

Altered homeostasis of CD4+ FoxP3+ regulatory Tcell subpopulations in systemic lupus erythematosus

JL Suen, HT Li, YJ Jong, BL Chiang, JH Yen - Immunology, 2009 - Wiley Online Library
regulatory T cells (Treg), known to be phenotypically heterogeneous, in controlling the expression
of systemic lupus erythematosus (… CD4 + CD25 high T cells were sorted and examined …

… CD4+,CD25− T cell sensitivity to the suppressive function of CD4+,CD25high,CD127−/low regulatory T cells in patients with active systemic lupus erythematosus

RK Chowdary Venigalla, T Tretter… - … : Official Journal of …, 2008 - Wiley Online Library
T cell proliferation in regulatory T (Treg) cell assays with cells from patients with active systemic
lupus erythematosus (… CD4+,CD25− responder T (Tresp) cells (5 × 10 3 /well) and CD4+,…

Inverse correlation between CD4+ regulatory Tcell population and autoantibody levels in paediatric patients with systemic lupus erythematosus

JH Lee, LC Wang, YT Lin, YH Yang, DT Lin… - …, 2006 - Wiley Online Library
lupus erythematosus (SLE), an autoimmune disease characterized by inappropriate regulation
of hyperactivated B and T cells… Using flow cytometry to determine cell populations and real…