… Regulatory T cells (Tregs) are a type of cells that are essential for controlling self-antigen
reactive T cells and inducing peripheral tolerance in vivo. The transcription factor Foxp3 …

… , leading to abnormal regulatory T-cell (Treg) … + T cells and influences IL-2 response
and T helper cell differentiation. SLAMF3 ligation promotes T-cell responses to IL-2 via up-regulation …

… lupus erythematosus (SLE) is a chronic autoimmune disease affecting various organs.
Decreased numbers of regulatory T-cells (Treg cells; … was observed in many lupus patients. In the …

… primed and expanded with TGF-β have the potential to be used as a therapy for patients
with systemic lupus erythematosus and other chronic inflammatory diseases. This novel …

… Systemic lupus erythematosus (SLE) is associated with an IL-2–deficient state, with regulatory
T cells (Tregs) showing diminished immune regulatory capacity. A low dose of IL-2 has …

… , and follicular helper cells. SLE CD4 + T cells are known to provide help to B cells, produce
… In the absence of sufficient amounts of IL-2, regulatory T cells, do not function properly to …

… that a subset of CD4 + T cells with regulatory capacity (regulatory T cells; T regs ) can function
to … of thymic-derived T regs play a role in systemic lupus erythematosus, we evaluated …

… + T cells resembled regulatory T cells rather than activated T … cells in patients with systemic
lupus erythematosus (SLE) as … Since increased levels of activated T cells due to chronic T cell …

… (E) Frequency of FOXP3 + cells from either the CD127 low CD25 hi or CD127 low CD25 low
populations in each identified regulatory T cell (Treg) or effector T cell (Teff) cluster. Clusters …

… expressed on CD4+CD25+T cells. FoxP3 has been described … of CD4+CD25highFoxP3+
regulatory T cells can play a key … CD4+CD25+ regulatory T cells in patients with SLE and to …