… Tregs without perturbing effector T cell function or immune … regulatory networks that modulate
Treg function and identify biomarkers that define functionally suppressive regulatory T cell …

… In this context, immunosuppressive cells, including regulatory T cells (Tregs) and myeloid-derived
suppressor cells (MDSCs), have come under intense investigation for their proposed …

… therapeutic targets but would also likely inform clinical trial design and highlight additional
biomarkers that could be used to assess T reg -cell function and fate following therapeutic …

… Regulatory T cells (T REG ) are a subset of CD4 + T cells with a critical role in the prevention
of autoimmunity. Whether defects in T REG contribute to the pathogenesis of rheumatoid …

… of Treg cells into the tumor microenvironment (TME) occurs in multiple murine and human
tumors. Regulatory T cells … Regulatory T cells are then activated and inhibit antitumor immune …

… of atherosclerosis; thus, a potential therapeutic target involves an increase in Tregs. Recent
… Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages …

… discovery of CD4 + regulatory T cells expressing the transcription factor … T cells and immune
regulatory Treg populations. A beneficial immune response warrants the timely regulation by …

… suppressive functions of FOXP3 + regulatory T cells. Understanding which HDACs contribute
to the regulation of the functions of regulatory T cells may further stimulate the development …

… with high numbers of FoxP3 cells. These results argue that regulatory T cells may play a role
in … aggressive breast carcinomas, and are a potential therapeutic target for these cancers. …

… Regulatory T cells (Treg) are an immunosuppressive subtype of CD4 + T cells essential for
… Hence, therapeutic targeting of Tregs may impede immunosuppressive cellular crosstalk …