Regulatory T cells in autoimmune disease

M Dominguez-Villar, DA Hafler - Nature immunology, 2018 - nature.com
Tissue-resident T reg cells actively perform non-immunological functions and work at …
tissue homeostasis and wound repair, roles that could be important for tissue homeostasis in …

Immune homeostasis enforced by co-localized effector and regulatory T cells

Z Liu, MY Gerner, N Van Panhuys, AG Levine… - Nature, 2015 - nature.com
regulatory T cells (T reg cells) prevent autoimmunity by limiting the effector activity of T cells
… function of T reg cells, the relevant cellular events in intact tissues remain largely unexplored…

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

…, H Mouquet, GD Victora, T Eisenreich… - Journal of Experimental …, 2009 - rupress.org
… loss of T reg cells, we complemented DC-depleted mice by injection of CD4 + CD25 +
regulatory T cells six hours after each DT injection. We found that injection of T reg cells prevented …

Control of intestinal homeostasis by regulatory T cells and dendritic cells

JL Coombes, KJ Maloy - Seminars in immunology, 2007 - Elsevier
… Here we have highlighted the roles of dendritic cells and regulatory T cells in the control of
deleterious inflammatory responses in the intestine. It is clear however, that they themselves …

Control of homeostatic proliferation by regulatory T cells

S Shen, Y Ding, CE Tadokoro… - The Journal of …, 2005 - Am Soc Clin Investig
… (33) and influences T cell repertoire in rheumatoid arthritis (34). In … homeostatic expansion
of a polyclonal T cell population within lymph nodes (35). In transplantation, allospecific T cells

[HTML][HTML] Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells

J Seneschal, RA Clark, A Gehad, CM Baecher-Allan… - Immunity, 2012 - cell.com
… resident memory T cells, including various helper, cytotoxic, and regulatory T cell subsets,
that are poised to respond to environmental antigens. Using only autologous human tissues, …

Dendritic cells coordinate the development and homeostasis of organ-specific regulatory T cells

DS Leventhal, DC Gilmore, JM Berger, S Nishi, V Lee… - Immunity, 2016 - cell.com
Regulatory T cells prevent catastrophic autoimmunity … Analysis of APC types involved in
CD4 tolerance and regulatory T cell … of regulatory T cell homeostasis by dendritic cells in vivo. …

A distinct function of regulatory T cells in tissue protection

N Arpaia, JA Green, B Moltedo, A Arvey, S Hemmers… - Cell, 2015 - cell.com
Regulatory T (Treg) cells suppress immune responses to a broad range … tissue damage by
employing multiple mechanisms of suppression. Here, we demonstrate that selective Treg cell

Thymic development and peripheral homeostasis of regulatory T cells

A Liston, AY Rudensky - Current opinion in immunology, 2007 - Elsevier
… impairment is caused by a cell-intrinsic effect in differentiating T-reg precursor cells versus
a deficiency in interleukin 2 (IL-2) production by non-regulatory T cells. The latter possibility …

Migration and homeostasis of regulatory T cells in rheumatoid arthritis

K Kotschenreuther, S Yan, DM Kofler - Frontiers in Immunology, 2022 - frontiersin.org
regulatory T cells are a distinct T cell subpopulation involved in the maintenance and regulation
of self-tolerance and homeostasis… + T cells as well as naïve resting regulatory T cells can …