… We hypothesized that Tregs are dysfunctional in ischemic cardiomyopathy and HF, and they
… CD4 + T cells, as we have shown cardiac profibrotic effects of splenic CD4 + T cells from …

… regulatory T cells (Tregs) that globally suppress the activation of immune responses. Given
that ischemic … Therefore, we propose that ischemic cardiomyopathy should be thought of, in …

… Following ischemic injury, immune cells infiltrate tissues and produce inflammatory … to
the development of diverse ischemic diseases including ischemic heart disease (IHD) [1], …

… regulatory Tregs might have a major impact on the limitation of inflammation-triggered local
tissue damage, cardiac … Therefore, we aimed to investigate the impact of regulatory T cells on …

… , dilated cardiomyopathy (DCM), and ischemic HF (37–40)… ischemic HFrEF patients (42).
Except for the change in Treg number, the suppression function of Tregs on conventional T cells …

… Follicular regulatory T cells (Tfr) have critical functions in … Tfr cell frequency in patients with
dilated cardiomyopathy (DCM)… DCM cases showed markedly reduced Tfr cell rates and Tfr/Tfh …

… severity and prevent transition to inflammatory dilated cardiomyopathy. Interestingly, recent
… in myocarditis. These subsets include Th1 and Th17 effector cells and regulatory T cells, …

… We demonstrate that regulatory T cells (Tregs) that accumulate in the injured myocardium
after myocardial infarction (MI) or myocardial ischemia/reperfusion injury have a distinct …

… of coronary atherosclerosis and the occurrence of ischemic heart disease (IHD). Regulatory
T cells (Tregs) play an essential regulatory role in atherosclerotic plaque formation and …

… in the pathogenesis of chronic heart failure (CHF). Regulatory T cells appear central to the
… dilated cardiomyopathy (DCM) showed infiltration of T cells and transfer of peripheral blood …