… reinforcing effects of several different classes of stimuli. The DA hypothesis of reinforcement
… hypothesis of reinforcement is that DA neurons constitute a critical link in the brain's natural …

… The possibility that morphine exerts its reinforcing effects via an action in the nucleus
accumbens was investigated in the rat using the self-administration model and the method of …

… a reinforcing effect could be an emergent property that results from the modulation of various
channels of information passing through the nucleus accumbens. … to natural reinforcement; …

… Indeed, the meso-accumbens DA system appears to play a critical role in mediating reinforcing
effects of these psychomotor-stimulants (for review, see Refs. 133, 297). Depletion of DA …

… The nucleus accumbens, a site within the ventral striatum, is best known for its prominent
role in mediating the reinforcing effects of … A basic rule of positive reinforcement is that motor …

… reinforcing. However, little is known about the specific cellular and molecular mechanisms
mediating sexual reward or the reinforcing effects … role in the reinforcement of sexual behavior …

… effects and the nucleus accumbens dopamine system is the important site of action for the
drug's positive reinforcing effects… aversive and positive reinforcing effects, respectively. Neither …

… reinforcing effects of heroin in non-dependent rats intravenously self-administering heroin.
Injections of the hydrophilic opiate antagonist methylnaloxonium into the nucleus accumbens …

… In summary, we showed that mesocorticolimbic DA is involved in the positively reinforcing
effects of agonistic encounters. The localized microinjection technique we used was …

… and the nucleus accumbens (NAc), a brain region also implicated in positive reinforcement.
We … help to refine our understanding of the neural circuitry mediating positive reinforcement. …