… In addition, a correlation between local IgM synthesis and myelin basic protein concentration…
CSF of patients with MS.7 Moreover, we have reported that intrathecal IgM synthesis (ITMS) …

… of IgM-OCB in both study groups. In addition, we did not find any association between
increased IgM-Index values and the frequency of relapses or a shorter time span for a relapse. In …

… IgM synthesis (ITMS) … relapsing-remitting MS patients for a longer time to evaluate whether
the ITMS implies a poor prognosis. Oligoclonal IgM bands were performed in 29 MS patients …

… In our cohort, a similar proportion of patients received a DMT before the second relapse, and
ITMS remained significant, also including in the multivariable model DMT exposition before …

… IgM synthesis in 16 patients in this report where the IgM response remains constant in the
individual patient … in children with MS correlates with a lower relapse rate in the first two years. …

… plied to the determination of IgA, IgM and IgD levels in the cerebrospinal fluid and plasma
from a group of 61 consecutive MS patients (41 relapsing-remitting and 20 secondary chronic …

… When we analyzed EDSS score in the different MS groups classified according to disease
duration, we found no differences between the group of first relapse patients with and without …

… We found that patients with LS-OCMBs developed a second relapse earlier than those
without LS-OCMBs. Differences were more significant than those obtained when comparing …

… predictive values of about 75% for intrathecal IgM synthesis and 50% for the CSF IgM
concentration and the LATEX/IgM test are influenced by the high relapse rate found in this study. …

… IgM synthesis (presence of IgM-OCB in the CSF) does not correlate with the risk of relapse in
patients … demonstrated that intrathecal IgM synthesis is not a negative prognostic marker of …