In the absence of pathognomonic signs, the diagnosis of filarial infections relies on
geographical exposure and morphology of microfilariae, which requires expertise. We …

Background The wide distribution of Loa loa infection (loiasis) throughout the Democratic
Republic of Congo (DRC) is a major obstacle to the plans to eliminate onchocerciasis and …

Background Immunochromatographic card test (ICT) is a tool to map the distribution of
Wuchereria bancrofti. In areas highly endemic for loaisis in DRC and Cameroon, a …

Accurate and specific diagnosis of human loiasis is of crucial importance in an endemic area
where two-thirds of infected individuals are without circulating microfilariae (occult loiasis) …

Filarial parasites infect an estimated 140 million people worldwide. Wuchereria bancrofti,
Onchocerca volvulus, Loa loa and Mansonella perstans are responsible for most filarial …

It is well known that renal and neurological complications may occur after antifilarial
treatment of patients infected with Loa loa. Conversely, spontaneous cases of visceral …

Background Mapping of lymphatic filariasis (LF) caused by Wuchereria bancrofti largely
relies on the detection of circulating antigen using ICT cards. Several studies have recently …

Implementation of mass drug administration for lymphatic filariasis (LF) has been delayed in
central Africa because of incomplete mapping and coendemic loiasis. We mapped two …

Background Human filarial infection is characterized by downregulated parasite-antigen
specific T cell responses but distinct differences exist between patients with longstanding …

Ivermectin treatment may induce marked adverse effects in those harbouring> 8000 Loa
microfilariae (mff)/ml of blood, individuals with> 30 000 Loa mff/ml being at risk of developing …