Post-GWAS in prostate cancer: from genetic association to biological contribution
Genome-wide association studies (GWAS) have been successful in deciphering the genetic
component of predisposition to many human complex diseases including prostate cancer …
component of predisposition to many human complex diseases including prostate cancer …
A review of prostate cancer genome-wide association studies (GWAS)
S Benafif, Z Kote-Jarai, RA Eeles - Cancer Epidemiology, Biomarkers & …, 2018 - AACR
Prostate cancer is the most common cancer in men in Europe and the United States. The
genetic heritability of prostate cancer is contributed to by both rarely occurring genetic …
genetic heritability of prostate cancer is contributed to by both rarely occurring genetic …
Comprehensive functional annotation of 77 prostate cancer risk loci
DJ Hazelett, SK Rhie, M Gaddis, C Yan… - PLoS …, 2014 - journals.plos.org
Genome-wide association studies (GWAS) have revolutionized the field of cancer genetics,
but the causal links between increased genetic risk and onset/progression of disease …
but the causal links between increased genetic risk and onset/progression of disease …
[HTML][HTML] H3K27ac HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility
C Giambartolomei, JH Seo, T Schwarz… - The American Journal of …, 2021 - cell.com
Genome-wide association studies (GWASs) have identified more than 200 prostate cancer
(PrCa) risk regions, which provide potential insights into causal mechanisms. Multiple lines …
(PrCa) risk regions, which provide potential insights into causal mechanisms. Multiple lines …
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
A Amin Al Olama, T Dadaev, DJ Hazelett… - Human molecular …, 2015 - academic.oup.com
Genome-wide association studies (GWAS) have identified numerous common prostate
cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the …
cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the …
A systematic review of replication studies of prostate cancer susceptibility genetic variants in high-risk men originally identified from genome-wide association studies
MB Ishak, VN Giri - Cancer epidemiology, biomarkers & prevention, 2011 - AACR
Background: Several prostate cancer genome-wide association studies (GWAS) have
identified risk-associated genetic variants primarily in populations of European descent …
identified risk-associated genetic variants primarily in populations of European descent …
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
T Dadaev, EJ Saunders, PJ Newcombe… - Nature …, 2018 - nature.com
Prostate cancer is a polygenic disease with a large heritable component. A number of
common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here …
common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here …
Genome-wide association study identifies new prostate cancer susceptibility loci
FR Schumacher, SI Berndt, A Siddiq… - Human molecular …, 2011 - academic.oup.com
Prostate cancer (PrCa) is the most common non-skin cancer diagnosed among males in
developed countries and the second leading cause of cancer mortality, yet little is known …
developed countries and the second leading cause of cancer mortality, yet little is known …
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
Prostate cancer genomics, biology, and risk assessment through genome‐wide association studies
H Nakagawa, S Akamatsu, R Takata… - Cancer …, 2012 - Wiley Online Library
Prostate cancer (PC) is the most common malignancy observed in men. It is evident that
genetic factors play some important roles in PC etiology. Recently, genome‐wide …
genetic factors play some important roles in PC etiology. Recently, genome‐wide …