Intensity-modulated radiotherapy significantly reduces xerostomia compared with conventional radiotherapy

PM Braam, CHJ Terhaard, JM Roesink… - International Journal of …, 2006 - Elsevier
Purpose: Xerostomia is a severe complication after radiotherapy for oropharyngeal cancer,
as the salivary glands are in close proximity with the primary tumor. Intensity-modulated …

Protection of salivary function by intensity-modulated radiation therapy in patients with head and neck cancer

KSC Chao - Seminars in Radiation Oncology, 2002 - Elsevier
The degree of xerostomia has been reported to depend on the radiation dose and the
salivary gland volume irradiated. Sparing salivary function can be achieved by reducing …

A novel dose constraint to reduce xerostomia in head-and-neck cancer patients treated with intensity-modulated radiotherapy

L Strigari, M Benassi, G Arcangeli, V Bruzzaniti… - International Journal of …, 2010 - Elsevier
PURPOSE: To investigate the predictors of incidence and duration of xerostomia (XT) based
on parotid glands (PG), submandibular glands (SMG), and both glands taken as a whole …

Intensity modulated radiotherapy for head and neck cancer: evidence for preserved salivary gland function

K Saarilahti, M Kouri, J Collan, T Hämäläinen… - Radiotherapy and …, 2005 - Elsevier
BACKGROUND AND PURPOSE: To investigate the salivary gland function following
intensity modulated radiotherapy (IMRT) for head and neck cancer. PATIENTS AND …

Importance of the initial volume of parotid glands in xerostomia for patients with head and neck cancers treated with IMRT

Y Nishimura, K Nakamatsu, T Shibata… - Japanese journal of …, 2005 - academic.oup.com
Objective: Our aim was to evaluate predictors of xerostomia in patients with head and neck
cancers treated with intensity-modulated radiation therapy (IMRT). Methods: Thirty-three …

Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer

A Eisbruch, HM Kim, JE Terrell, LH Marsh… - International Journal of …, 2001 - Elsevier
Purpose: To assess long-term xerostomia in patients receiving parotid-sparing radiation
therapy (RT) for head-and-neck cancer, and to find the patient and therapy-related factors …

Intensity-modulated radiotherapy: Is xerostomia still prevalent?

MS Chambers, AS Garden, D Rosenthal… - Current oncology …, 2005 - Springer
Conformal radiation with intensity-modulated radiotherapy (IMRT) is a technique that
potentially can minimize the dose to salivary glands and thereby decrease the incidence of …

A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial …

KSC Chao, JO Deasy, J Markman, J Haynie… - International Journal of …, 2001 - Elsevier
Objectives: In a prospective clinical study, we tested the hypothesis that sparing the parotid
glands may result in significant objective and subjective improvement of xerostomia in …

The effect of parotid gland‐sparing intensity‐modulated radiotherapy on salivary composition, flow rate and xerostomia measures

TM Richards, T Hurley, L Grove, KJ Harrington… - Oral …, 2017 - Wiley Online Library
Objectives To describe parotid gland (PG) saliva organic and inorganic composition and
flow rate changes, after curative intensity‐modulated radiotherapy (IMRT) for head and neck …

Sparing of the submandibular glands by intensity modulated radiotherapy in the treatment of head and neck cancer

K Saarilahti, M Kouri, J Collan, A Kangasmäki… - Radiotherapy and …, 2006 - Elsevier
BACKGROUND AND PURPOSE: The submandibular glands produce most of the
unstimulated saliva output and are the key in prevention of radiation-related xerostomia. We …