A conserved and immunodominant lipoprotein of Francisella tularensis is proinflammatory but not essential for virulence

CA Forestal, H Gil, M Monfett, CE Noah, GJ Platz… - Microbial …, 2008 - Elsevier
Francisella tularensis is a highly virulent bacterium that causes tularemia, a disease that is
often fatal if untreated. A live vaccine strain (LVS) of this bacterium is attenuated for virulence …

Grey variants of the live vaccine strain of Francisella tularensis lack lipopolysaccharide O-antigen, show reduced ability to survive in macrophages and do not induce …

G Hartley, R Taylor, J Prior, S Newstead, PG Hitchen… - Vaccine, 2006 - Elsevier
Francisella tularensis live vaccine strain (LVS) produces two colony types when grown on
solid media, often referred to as blue variants (BV) and grey variants (GV). Whereas blue …

Francisella tularensis as a potential agent of bioterrorism?

M Maurin - Expert Review of Anti-Infective Therapy, 2015 - Taylor & Francis
Francisella tularensis is a category A bioterrorism agent. It is the etiological agent of
tularemia, a zoonotic disease found throughout the northern hemisphere. The intentional …

Tularemia (Francisella tularensis)

M Forsman, A Johansson - Encyclopedia of bioterrorism …, 2005 - Wiley Online Library
Tularemia is a zoonosis, a disease of animals transmissible to humans, and is caused by the
facultative intracellular bacterium Francisella tularensis. F. tularensis is considered a …

Development of a Multivalent Subunit Vaccine against Respiratory Tularemia

AA Mansour, S Banik, M Malik… - The Journal of …, 2017 - journals.aai.org
Francisella tularensis (Ft); the causative agent of a fatal human disease tularemia is
classified as a Category A Select Agent. No licensed vaccine is available for prevention of …

Evaluation of Francisella tularensis ΔpdpC as a candidate live attenuated vaccine against respiratory challenge by a virulent SCHU P9 strain of Francisella tularensis …

D Tian, A Uda, E Park, A Hotta, O Fujita… - Microbiology and …, 2018 - Wiley Online Library
Francisella tularensis, which causes tularemia, is an intracellular gram‐negative bacterium.
F. tularensis has received significant attention in recent decades because of its history as a …

Susceptibility of various mouse strains to systemically-or aerosol-initiated tularemia by virulent type A Francisella tularensis before and after immunization with the …

H Shen, W Chen, JW Conlan - Vaccine, 2004 - Elsevier
The following study determined whether commonly available mouse strains could be used
to reveal vaccines capable of protecting against aerosol exposure to virulent type A strains …

Francisella tularensis: biology, pathogenicity, epidemiology, and biodefense

L Eisen - Emerging Infectious Diseases, 2007 - ncbi.nlm.nih.gov
Pathogenicity, Epidemiology, and Biodefense, published by Blackwell Publishing Limited on
behalf of the New York Academy of Sciences. This book is a much-needed comprehensive …

[HTML][HTML] The Francisella Tularensis Proteome and its Recognition by Antibodies

SLN Kilmury, SM Twine - Frontiers in microbiology, 2011 - frontiersin.org
Francisella tularensis is the causative agent of a spectrum of diseases collectively known as
tularemia. The extreme virulence of the pathogen in humans, combined with the low …

Identification of immunologic and pathologic parameters of death versus survival in respiratory tularemia

D Chiavolini, J Alroy, CA King, P Jorth… - Infection and …, 2008 - Am Soc Microbiol
Francisella tularensis can cause severe disseminated disease after respiratory infection.
The identification of factors involved in mortality or recovery following induction of tularemia …