Background Reduced-antigen-content tetanus, diphtheria, and acellular pertussis (Tdap)
vaccine is recommended in many countries for boosting immunity in adolescents and adults …

Background. Pertussis is increasingly recognized as an important cause of cough illness in
adolescents and adults. Purpose. To evaluate the safety and antibody response to a single …

OBJECTIVE: The safety of a booster dose of a reduced-antigen-content tetanus–diphtheria–
acellular pertussis (Tdap) vaccine was evaluated in adolescents previously vaccinated with …

Objective. We compared the diphtheria and tetanus toxoids and bicomponent acellular
pertussis vaccine (DTaP) responses in Japanese and United States infants. Design. This …

ABSTRACT Background: An acellular Pertussis (aP) vaccine containing recombinant
genetically detoxified Pertussis Toxin (PTgen), Filamentous Hemagglutinin (FHA) and …

Purpose Despite high national vaccination coverage with tetanus toxoid, reduced diphtheria
toxoid, and acellular pertussis (Tdap) vaccines among US adolescents, rates of adolescent …

Annual vaccination with trivalent influenza vaccine (TIV), and a single dose of tetanus toxoid-
reduced diphtheria toxoid-acellular pertussis (Tdap) vaccine, are both recommended for …

The widespread use of whole-cell pertussis vaccines in the second half of the 20th century
have reduced the incidence of the disease significantly. However, in some countries …

Background. Diphtheria and tetanus toxoid combined with acellular pertussis (DTaP)
vaccines are less reactogenic than diphtheria and tetanus toxoid combined with whole cell …

Background: Real evaluation of any vaccine can only be done after the vaccine has been in
routine use for a substantially long period of time. In Japan, acellular pertussis vaccine was …