ZINC is one of the most abundant of the essential trace elements in the human body. Its
concentration in soft tissues is in the same range as that of iron. All living organisms require …

(Received for publication Dec. 30, 1960) w HILE analyzing human organs for trace metals,
one of us (Tipton) observed surprisingly large amounts of cadmium in the kidney.'This …

Most human subjects dying from hypertensive complications showed in their kidneys either
increased concentrations of cadmium or increased ratios of cadmium to zinc, compared to …

Dietary depletion of zinc was found to result in a 30% decrease in the total body zinc content
of experimental rats when compared with control animals. In the depleted animals there was …

The 1934 report by Todd et al.(300) that zinc was necessary for life in animals suggested
that it was probably an essential nutrient for man also. Nevertheless the ubiquity of zinc …

Zinc is one of the so-called trace elements present in the body, but in nature it is present in
the Earth's crust to the extent of about 0.02% and is 23rd in the order of abundance of the …

More than 40 years have elapsed since zinc was shown to be an essential element for
animals (155) but its importance in human nutrition has only recently become widely …

The present explosion in knowledge of zinc has been the result of several factors, the major
ones being the recognition of the important role of zinc in human health and diseases, its …

The pervasive role of zinc in the metabolic function of the body results from its function as a
cofactor of a multitude of enzymes. Zinc is found in every tissue in the body, and because …

During the past two decades, the essentiality of zinc for man has been established.
Deficiency of zinc in man due to nutritional factors and several diseased states has been …