Bacterial membrane vesicles in the pathogenesis and treatment of inflammatory bowel disease

CV Olovo, DK Wiredu Ocansey, Y Ji, X Huang… - Gut Microbes, 2024 - Taylor & Francis
Inflammatory bowel disease (IBD) is a chronic and debilitating condition of relapsing and
remitting inflammation in the gastrointestinal tract. Conventional therapeutic approaches for …

Bacterial membrane vesicles in inflammatory bowel disease

Q Shen, B Xu, C Wang, Y Xiao, Y Jin - Life sciences, 2022 - Elsevier
Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation with no
cure. The intestine is fundamental in controlling human health. Disruption of the microbial …

[HTML][HTML] Characterization of feces-derived bacterial membrane vesicles and the impact of their origin on the inflammatory response

N Kameli, R Borman, C López-Iglesias… - Frontiers in Cellular …, 2021 - frontiersin.org
The human gastrointestinal tract harbors a diverse and complex microbiome, which interacts
in a variety of ways with the host. There is compelling evidence that gut microbial dysbiosis …

Therapeutic Applications of Extracellular Vesicles in Inflammatory Bowel Disease

SH Kim, B Keum, S Kwak, J Byun, JM Shin… - International journal of …, 2024 - mdpi.com
The treatment landscape for inflammatory bowel disease (IBD) has undergone substantial
advancements with the introduction of biologics. However, a considerable number of …

Extracellular vesicles and their indispensable roles in pathogenesis and treatment of inflammatory bowel disease: A comprehensive review

L Chen, Q Ou, X Kou - Life Sciences, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a global disease with rising incidence worldwide, and
its debilitating symptoms and dissatisfactory therapies have brought heavy burdens for …

Bacterial extracellular vesicles and their interplay with the immune system

E Doré, E Boilard - Pharmacology & Therapeutics, 2023 - Elsevier
The mammalian intestinal tract harbors trillions of microorganisms confined within this space
by mucosal barriers. Despite these barriers, bacterial components may still be found …

Extracellular vesicles in inflammatory bowel disease: small particles, big players

M Valter, S Verstockt, JA Finalet Ferreiro… - Journal of Crohn's …, 2021 - academic.oup.com
Extracellular vesicles are nanovesicles released by many cell types into the extracellular
space. They are important mediators of intercellular communication, enabling the functional …

[HTML][HTML] The role and mechanisms of gram-negative bacterial outer membrane vesicles in inflammatory diseases

S Chen, Q Lei, X Zou, D Ma - Frontiers in Immunology, 2023 - frontiersin.org
Outer membrane vesicles (OMVs) are spherical, bilayered, and nanosized membrane
vesicles that are secreted from gram-negative bacteria. OMVs play a pivotal role in …

[HTML][HTML] From trash to treasure: the role of bacterial extracellular vesicles in gut health and disease

D Sun, P Chen, Y Xi, J Sheng - Frontiers in Immunology, 2023 - frontiersin.org
Bacterial extracellular vesicles (BEVs) have emerged as critical factors involved in gut health
regulation, transcending their traditional roles as byproducts of bacterial metabolism. These …

[HTML][HTML] The role of bacterial membrane vesicles in human health and disease

DN Villageliu, DR Samuelson - Frontiers in Microbiology, 2022 - frontiersin.org
Bacterial membrane vesicles (MVs) are nanoparticles derived from the membrane
components of bacteria that transport microbial derived substances. MVs are ubiquitous …