Overcoming rest–task divide—abnormal temporospatial dynamics and its cognition in schizophrenia
G Northoff, J Gomez-Pilar - Schizophrenia bulletin, 2021 - academic.oup.com
Schizophrenia is a complex psychiatric disorder exhibiting alterations in spontaneous and
task-related cerebral activity whose relation (termed “state dependence”) remains unclear …
task-related cerebral activity whose relation (termed “state dependence”) remains unclear …
Associative deficit accounts of disrupted latent inhibition and blocking in schizophrenia
Latent inhibition (attenuated responding to a signal due to signal-alone presentations
preceding the signal-outcome pairings) and blocking (attenuated responding to Signal B …
preceding the signal-outcome pairings) and blocking (attenuated responding to Signal B …
Frontal–striatal–thalamic mediodorsal nucleus dysfunction in schizophrenia-spectrum patients during sensorimotor gating
EA Hazlett, MS Buchsbaum, J Zhang, RE Newmark… - Neuroimage, 2008 - Elsevier
Prepulse inhibition (PPI) refers to a reduction in the amplitude of the startle eyeblink reflex to
a strong sensory stimulus, the pulse, when it is preceded shortly by a weak stimulus, the …
a strong sensory stimulus, the pulse, when it is preceded shortly by a weak stimulus, the …
Neural oscillatory deficits in schizophrenia predict behavioral and neurocognitive impairments
Paying attention to visual stimuli is typically accompanied by event-related
desynchronizations (ERD) of ongoing alpha (7–14 Hz) activity in visual cortex. The present …
desynchronizations (ERD) of ongoing alpha (7–14 Hz) activity in visual cortex. The present …
Neural correlates of impaired cognitive control over working memory in schizophrenia
Background One of the most common deficits in patients with schizophrenia (SZ) is in
working memory (WM), which has wide-reaching impacts across cognition. However …
working memory (WM), which has wide-reaching impacts across cognition. However …
Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review
MA Geyer, K Krebs-Thomson, DL Braff… - …, 2001 - Springer
Rationale: Patients with schizophrenia exhibit deficits in an operational measure of
sensorimotor gating: prepulse inhibition (PPI) of startle. Similar deficits in PPI are produced …
sensorimotor gating: prepulse inhibition (PPI) of startle. Similar deficits in PPI are produced …
Prepulse inhibition of the startle response in risperidone-treated patients: comparison with typical antipsychotics
V Kumari, W Soni, T Sharma - Schizophrenia Research, 2002 - Elsevier
Individuals with schizophrenia are known to show deficits in prepulse inhibition (PPI) of the
startle response. PPI refers to a response suppression in reaction to a strong startling …
startle response. PPI refers to a response suppression in reaction to a strong startling …
Reduced prepulse inhibition as a biomarker of schizophrenia
A Mena, JC Ruiz-Salas, A Puentes, I Dorado… - Frontiers in behavioral …, 2016 - frontiersin.org
The startle response is composed by a set of reflex behaviors intended to prepare the
organism to face a potentially relevant stimulus. This response can be modulated by several …
organism to face a potentially relevant stimulus. This response can be modulated by several …
[HTML][HTML] Brain rhythms connect impaired inhibition to altered cognition in schizophrenia
In recent years, schizophrenia research has focused on inhibitory interneuron dysfunction at
the level of neurobiology and on cognitive impairments at the psychological level …
the level of neurobiology and on cognitive impairments at the psychological level …
Reversal of evoked gamma oscillation deficits is predictive of antipsychotic activity with a unique profile for clozapine
Recent heuristic models of schizophrenia propose that abnormalities in the gamma
frequency cerebral oscillations may be closely tied to the pathophysiology of the disorder …
frequency cerebral oscillations may be closely tied to the pathophysiology of the disorder …