Response inhibition and response monitoring in a saccadic countermanding task in schizophrenia
BACKGROUND:: Cognitive control deficits are pervasive in individuals with schizophrenia
(SZ) and are reliable predictors of functional outcome, but the specificity of these deficits and …
(SZ) and are reliable predictors of functional outcome, but the specificity of these deficits and …
Increased intra-individual variability of cognitive processing in subjects at risk mental state and schizophrenia patients
Intra-individual variability (IIV) has received recent attention as an indicator of the stability of
cognitive functioning that may outperform mean performance in reflecting putative …
cognitive functioning that may outperform mean performance in reflecting putative …
Prepulse inhibition and P50 suppression are both deficient but not correlated in schizophrenia patients
DL Braff, GA Light, NR Swerdlow - Biological psychiatry, 2007 - Elsevier
BACKGROUND: Inhibitory measures such as prepulse inhibition of the acoustic startle reflex
(PPI) and event related potential P50 suppression have been widely reported to show …
(PPI) and event related potential P50 suppression have been widely reported to show …
Neural correlates of positive and negative symptoms through the illness course: an fMRI study in early psychosis and chronic schizophrenia
Psychotic illness is associated with cognitive control deficits and abnormal recruitment of
neural circuits subserving cognitive control. It is unclear to what extent this dysfunction …
neural circuits subserving cognitive control. It is unclear to what extent this dysfunction …
Stop-signal task difficulty and the right inferior frontal gyrus
The stop-signal paradigm is increasingly being used as a probe of response inhibition in
basic and clinical neuroimaging research. The critical feature of this task is that a cued …
basic and clinical neuroimaging research. The critical feature of this task is that a cued …
Prepulse facilitation and prepulse inhibition in schizophrenia patients and their unaffected siblings
BACKGROUND: Deficits in schizophrenia patients and their first-degree relatives have been
reported in prepulse inhibition (PPI), a phenomenon that measures an early stage of …
reported in prepulse inhibition (PPI), a phenomenon that measures an early stage of …
Impaired prepulse inhibition of acoustic startle in schizophrenia
A Parwani, EJ Duncan, E Bartlett, SH Madonick… - Biological …, 2000 - Elsevier
Background: Schizophrenics show deficits in sensorimotor gating, as measured by prepulse
inhibition of acoustic startle (PPI). The goal of this investigation is to further characterize PPI …
inhibition of acoustic startle (PPI). The goal of this investigation is to further characterize PPI …
An fMRI study of reduced left prefrontal activation in schizophrenia during normal inhibitory function
K Rubia, T Russell, ET Bullmore, W Soni… - Schizophrenia …, 2001 - Elsevier
Functional magnetic resonance imaging (fMRI) was used to investigate the hypothesis that
schizophrenia is associated with a dysfunction of prefrontal brain regions during motor …
schizophrenia is associated with a dysfunction of prefrontal brain regions during motor …
[HTML][HTML] Cortical grey matter volume and sensorimotor gating in schizophrenia
Prepulse inhibition (PPI) of the startle response, a cross-species measure of sensorimotor
gating, provides a valuable tool to study the known inability of a large proportion of …
gating, provides a valuable tool to study the known inability of a large proportion of …
Assessing inhibitory control: a revised approach to the stop signal task
JD Carter, M Farrow, RB Silberstein… - Journal of attention …, 2003 - journals.sagepub.com
The stop signal task (stop task) is designed to assess inhibitory control and is a frequently
used research tool in clinical disorders such as ADHD and schizophrenia. Previous methods …
used research tool in clinical disorders such as ADHD and schizophrenia. Previous methods …