Symptom correlates of prepulse inhibition deficits in male schizophrenic patients

DL Braff, NR Swerdlow… - American Journal of …, 1999 - Am Psychiatric Assoc
OBJECTIVE: Information processing, inhibitory, and gating deficits in human and animal
model studies of schizophrenia are demonstrated by using prepulse inhibition of the startle …

Effects of typical and atypical antipsychotics on prepulse inhibition in schizophrenia: a critical evaluation of current evidence and directions for future research

V Kumari, T Sharma - Psychopharmacology, 2002 - Springer
Prepulse inhibition (PPI) of the startle response refers to an attenuation in response to a
strong stimulus (pulse) if this is preceded shortly by a weak non-startling stimulus (prepulse) …

[HTML][HTML] Knowing when to stop: Aberrant precision and evidence accumulation in schizophrenia

R Limongi, B Bohaterewicz, M Nowicka, A Plewka… - Schizophrenia …, 2018 - Elsevier
Predictive coding and active inference formulations of the dysconnection hypothesis suggest
that subjects with schizophrenia (SZ) hold unduly precise prior beliefs to compensate for a …

The relationship between sensorimotor gating and clinical improvement in acutely ill schizophrenia patients

A Minassian, D Feifel, W Perry - Schizophrenia research, 2007 - Elsevier
It has been suggested that sensorimotor gating deficits as indexed by prepulse inhibition
(PPI) of the acoustic startle reflex represent an endophenotypic marker of psychotic …

Disturbances in response inhibition and emotional processing as potential pathways to violence in schizophrenia: a high-density event-related potential study

MI Krakowski, P De Sanctis, JJ Foxe… - Schizophrenia …, 2016 - academic.oup.com
Objective: Increased susceptibility to emotional triggers and poor response inhibition are
important in the etiology of violence in schizophrenia. Our goal was to evaluate …

A topographic event-related potential follow-up study onprepulse inhibition'in first and second episode patients with schizophrenia

S Bender, U Schall, J Wolstein, I Grzella… - Psychiatry Research …, 1999 - Elsevier
Dopamine agonists impair and antagonists normalize prepulse inhibition (PPI) of startle and
gating of the P50 event-related potential (ERP), but the within-subject effect of treatment on …

Switching between univalent task-sets in schizophrenia: ERP evidence of an anticipatory task-set reconfiguration deficit

F Karayanidis, R Nicholson, U Schall, L Meem… - Clinical …, 2006 - Elsevier
OBJECTIVE: The present study used behavioral and event-related potential (ERP) indices of
task-switching to examine whether schizophrenia patients have a specific deficit in …

Sensorimotor gating deficits in schizophrenia: advancing our understanding of the phenotype, its neural circuitry and genetic substrates

NR Swerdlow, GA Light - Schizophrenia research, 2018 - Elsevier
In her 1936 report of paired-pulse blink inhibition in 13 Yale undergraduate men, Helen
Peak described “quantitative variation in amount of inhibition of the second response …

Response to the first stimulus determines reduced auditory evoked response suppression in schizophrenia: single trials analysis using MEG

LD Blumenfeld, BA Clementz - Clinical Neurophysiology, 2001 - Elsevier
Objective: Reduced auditory evoked response (AER) suppression in a paired-stimulus
paradigm may index genetic liability for schizophrenia. In most published studies of AER …

The effect of neuroleptic medication on prepulse inhibition in schizophrenia patients: current status and future issues

AO Hamm, AI Weike, HT Schupp - Psychopharmacology, 2001 - Springer
Rationale: Prepulse inhibition (PPI) of the startle reflex is a powerful tool for investigating
sensorimotor gating in both animals and humans. Evidence of impaired PPI in patients with …