Dissociation of the morphological correlates of stress‐induced anxiety and fear

JM Pego, P Morgado, LG Pinto… - European Journal of …, 2008 - Wiley Online Library
Chronic stress is a powerful modulator of emotional behaviour. Previous studies have
shown that distinct neuronal pathways modulate different emotional behaviours: while the …

Selective participation of the bed nucleus of the stria terminalis and CRF in sustained anxiety-like versus phasic fear-like responses

DL Walker, LA Miles, M Davis - Progress in Neuro-Psychopharmacology …, 2009 - Elsevier
The medial division of the central nucleus of the amygdala (CeAM) and the lateral division of
the bed nucleus of the stria terminalis (BNSTL) are closely related. Both receive projections …

Neuroanatomical and psychopharmacological evidence for interaction between opioid and GABAergic neural pathways in the modulation of fear and defense elicited …

GCD Eichenberger, SJ Ribeiro, MY Osaki… - …, 2002 - Elsevier
The effects of central administration of opioid antagonists on the aversive responses elicited
by electrical (at the freezing and escape thresholds) or chemical stimulation (crossings …

How many brain regions are needed to elucidate the neural bases of fear and anxiety?

L Pessoa - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
We suggest that to understand complex behaviors associated with fear and anxiety, we
need to understand brain processes at the collective, network level. But what should be the …

The Neurobiological Basis of Anxiety and Fear: Circuits, Mechanisms, and Neurochemical Interactions (Part I

DS Charney, C Grillon, JD Bremner - The Neuroscientist, 1998 - journals.sagepub.com
There have been tremendous advances in our knowledge of the neurobiological basis of
human anxiety and fear. This review seeks to highlight how specific neuronal circuits, neural …

Neurobiological bases of individual differences in emotional and stress responsiveness: high responders–low responders model

M Kabbaj - Archives of Neurology, 2004 - jamanetwork.com
Our understanding of the neurobiological bases of emotional responsiveness derives from 2
major classes of work. The first class represents studies interested in brain sites and …

Intrinsic neural circuits between dorsal midbrain neurons that control fear-induced responses and seizure activity and nuclei of the pain inhibitory system elaborating …

RL Freitas, CMR Ferreira, SJ Ribeiro, AD Carvalho… - Experimental …, 2005 - Elsevier
The blockade of GABA-mediated Cl− influx with pentylenetetrazol (PTZ) was used in the
present work to induce seizures in Rattus norvegicus. The aim of this work was to study the …

The neurobiology and control of anxious states

MJ Millan - Progress in neurobiology, 2003 - Elsevier
Fear is an adaptive component of the acute “stress” response to potentially-dangerous
(external and internal) stimuli which threaten to perturb homeostasis. However, when …

Excitotoxic lesions in the central nucleus of the amygdala attenuate stress-induced anxiety behavior

AP Ventura-Silva, A Melo, AC Ferreira… - Frontiers in behavioral …, 2013 - frontiersin.org
The extended amygdala, composed by the amygdaloid nuclei and the bed nucleus of the
stria terminalis (BNST), plays a critical role in anxiety behavior. In particular, the link between …

Contributions of the central extended amygdala to fear and anxietycontributions of the central extended amygdala to fear and anxiety

AJ Shackman, AS Fox - Journal of Neuroscience, 2016 - Soc Neuroscience
It is widely thought that phasic and sustained responses to threat reflect dissociable circuits
centered on the central nucleus of the amygdala (Ce) and the bed nucleus of the stria …