Neuroimaging of Alzheimer's disease: focus on amyloid and tau PET

H Matsuda, Y Shigemoto, N Sato - Japanese journal of radiology, 2019 - Springer
Although the diagnosis of dementia is still largely a clinical one, based on history and
disease course, neuroimaging has dramatically increased our ability to accurately diagnose …

[HTML][HTML] Advances in brain amyloid imaging

N Krishnadas, VL Villemagne, V Doré… - Seminars in nuclear …, 2021 - Elsevier
Amyloid-β (Aβ) PET imaging has now been available for over 15 years. The ability to detect
Aβ in vivo has greatly improved the clinical and research landscape of Alzheimer's disease …

Amyloid and tau PET imaging of Alzheimer disease and other neurodegenerative conditions

PA Rowley, AA Samsonov, TJ Betthauser… - Seminars in Ultrasound …, 2020 - Elsevier
Although diagnosing the syndrome of dementia is largely a clinical endeavor, neuroimaging
plays an increasingly important role in accurately determining the underlying etiology, which …

Neuroimaging in dementias

S Mahalingam, MK Chen - Seminars in Neurology, 2019 - thieme-connect.com
Dementia is a global health issue, the burden of which will worsen with an increasingly
aging population. Alzheimer's disease (AD) is the most common dementia, with 50 to 60% of …

Amyloid-β imaging with PET in Alzheimer's disease: is it feasible with current radiotracers and technologies?

MC Moghbel, B Saboury, S Basu, SD Metzler… - European journal of …, 2012 - Springer
Although it afflicts an estimated 26.6 million people worldwide—a figure that is expected to
quadruple by 2050—Alzheimer's disease (AD) has yet to be fully understood etiologically …

PET imaging of epigenetic influences on Alzheimer's disease

PJ Couto, RM Millis - International Journal of Alzheimer's …, 2015 - Wiley Online Library
The precise role of environment‐gene interactions (epigenetics) in the development and
progression of Alzheimer's disease (AD) is unclear. This review focuses on the premise that …

Applications of amyloid, tau, and neuroinflammation PET imaging to Alzheimer's disease and mild cognitive impairment

A Chandra, PE Valkimadi, G Pagano… - Human brain …, 2019 - Wiley Online Library
Alzheimer's disease (AD) is a devastating and progressive neurodegenerative disease for
which there is no cure. Mild cognitive impairment (MCI) is considered a prodromal stage of …

Amyloid PET and MRI in Alzheimer's disease and mild cognitive impairment

E Dimou, J Booij, M Rodrigues… - Current Alzheimer …, 2009 - ingentaconnect.com
The neurodegenerative disorder Alzheimer's disease (AD) is the most common form of
dementia. It is characterized by progressive impairment of cognitive functions and behavior …

Amyloid imaging

VL Villemagne, CC Rowe - International psychogeriatrics, 2011 - cambridge.org
Molecular neuroimaging techniques such as PET are proving valuable in the early and
differential diagnosis of Alzheimer's disease (AD). With the advent of new therapeutic …

PET imaging of tau pathology in Alzheimer's disease and tauopathies

OG James, PM Doraiswamy, S Borges-Neto - Frontiers in neurology, 2015 - frontiersin.org
Alzheimer's disease (AD) is a major public health problem affecting nearly 35 million people
worldwide with numbers projected to rise to 115.4 million by 2050. Medicare and Medicaid …