Preclinical imaging: an essential ally in modern biosciences

L Cunha, I Horvath, S Ferreira, J Lemos… - Molecular diagnosis & …, 2014 - Springer
Translational research is changing the practice of modern medicine and the way in which
health problems are approached and solved. The use of small-animal models in basic and …

State of the art in vivo imaging techniques for laboratory animals

DT Lauber, A Fülöp, T Kovács, K Szigeti… - Laboratory …, 2017 - journals.sagepub.com
In recent decades, imaging devices have become indispensable tools in the basic sciences,
in preclinical research and in modern drug development. The rapidly evolving high …

Technologies: preclinical imaging for drug development

PM Matthews, R Coatney, H Alsaid, B Jucker… - Drug Discovery Today …, 2013 - Elsevier
Preclinical imaging with magnetic resonance imaging (MRI), computerised tomography
(CT), ultrasound (US), positron emission tomography (PET) or single-photon emission …

Molecular imaging in living subjects: seeing fundamental biological processes in a new light

TF Massoud, SS Gambhir - Genes & development, 2003 - genesdev.cshlp.org
Morphological observations have driven the course of biology ever since the first
microscope was built in the late sixteenth century. Molecular imaging is a rapidly emerging …

Small animal imaging in drug development

MG Pomper, JS Lee - Current pharmaceutical design, 2005 - ingentaconnect.com
Better mechanistic understanding of disease through mapping of the human and mouse
genomes enables rethinking of human infirmity. In the case of cancer, eg, we may begin to …

[图书][B] Handbook of small animal imaging: preclinical imaging, therapy, and applications

GC Kagadis, NL Ford, DN Karnabatidis, GK Loudos - 2016 - books.google.com
The use of small animal models in basic and preclinical sciences constitutes an integral part
of testing new pharmaceutical agents prior to their application in clinical practice. New …

Noninvasive imaging for supporting basic research

P Zanzonico - Small animal imaging: basics and practical guide, 2017 - Springer
By providing a noninvasive means of quantitatively assaying biological structure and
function in vivo, imaging of small laboratory animals (ie, mice and rats) has emerged as a …

In vivo small animal imaging: Current status and future prospects

GC Kagadis, G Loudos, K Katsanos… - Medical …, 2010 - Wiley Online Library
The use of small animal models in basic and preclinical sciences constitutes an integral part
of testing new pharmaceutical agents prior to commercial translation to clinical practice …

Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

Instrumentation for molecular imaging in preclinical research: Micro-PET and Micro-SPECT

AF Chatziioannou - Proceedings of the american thoracic society, 2005 - atsjournals.org
Noninvasive imaging of molecular events and interactions in living small animal models has
gained increasing importance in preclinical research. Two of the imaging modalities …