The description of neuroglia by Virchow in 1848 may be considered the starting point of our
understanding of primary brain tumors. At the beginning of the 20th century, surgical …

Gliomas form a heterogeneous group of tumors of the central nervous system (CNS) and are
traditionally classified based on histologic type and malignancy grade. Most gliomas, the …

The modern clinical practice of neuro-oncology is dependent on accurate tumor
classification. No variable predicts prognosis more precisely, and classification is also the …

Primary brain tumors are classified according to the tissue of phylogenic origin. Tumors
arising from the neuroepithelium encompass a subgroup of neoplasms collectively referred …

This issue of the Journal of Neuro-Oncology is devoted to recent investigations of low-grade
gliomas. The purpose of this issue is not to debate the relative merits and liabilities of …

Cancer is a heterogeneous disease, which provides a broad field for investigation, while
simultaneously reducing the chances for a universal treatment. Malignant gliomas are the …

Abstract Rudolph Virchow (1821–1902), the founder of cellular pathology, already
separated gliomas from “psammomas,”“melanomas,” and other “sarcomas” of the nervous …

During the last decade, we have witnessed several key advances in the field of neuro-
oncology. First, there were conceptual advances in the molecular and cell biology of …

Gliomas are the most common form of malignant primary brain tumour. In the past year,
substantial progress has been made in the classification and treatment of lower-grade …

Glioma is the most common primary brain tumor, accounting for 30% to 40% of all
intracranial tumors. About half of all gliomas in adults are glioblastomas. Patients with …