In the last two decades, protein–protein interactions (PPIs) have been used as the main
target for drug development. However, with larger or superficial binding sites, it has been …

Self-binding peptides (SBPs) represent a novel biomolecular phenomenon spanning
between folding and binding, where a short peptide segment within a monomeric protein …

CABS-dock standalone is a multiplatform Python package for protein–peptide docking with
backbone flexibility. The main feature of the CABS-dock method is its ability to simulate …

As the protein databank (PDB) recently passed the cap of 123 456 structures, it stands more
than ever as an important resource not only to analyze structural features of specific …

Protein–protein interactions (PPIs) are implicated in the majority of cellular processes by
enabling and regulating the function of individual proteins. Thus, PPIs represent high-value …

AlphaFold has revolutionized structural biology by predicting highly accurate structures of
proteins and their complexes with peptides and other proteins. However, for protein‐peptide …

Phage display technology provides a versatile tool for exploring the interactions between
proteins, peptides and small molecule ligands. Quantitative analysis of peptide population …

Many biological activities originate from interactions between small-molecule ligands and
their protein targets. A detailed structural and physico-chemical characterization of these …

Modular protein interaction domains form the building blocks of eukaryotic signaling
pathways. Many of them, known as peptide recognition domains, mediate protein …