Background: The analgesic effects of celecoxib, a cyclooxygenase‐2 (COX‐2) inhibitor, on
formalin‐induced pain are still controversial. The purpose of this study was to examine the …

The non-steroidal anti-inflammatory drug celecoxib has long been used for reducing pain, in
spite of moderate gastrointestinal side effects. In previous studies, it has been shown that …

Celecoxib is a nonsteroidal anti-inflammatory drug (selective cyclooxygenase-2 inhibitor)
that is widely used. The efficacy and safety of celecoxib for treatment of acute postoperative …

Celecoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) and blocks prostaglandin
(PG) biosynthesis associated with inflammatory conditions. In a model of peripherally …

The peripheral antinociceptive effect of the selective COX-2 inhibitor celecoxib in the
formalin-induced inflammatory pain was compared with that of resveratrol (COX-1 inhibitor) …

The effects of selective cyclooxygenase-2 (COX-2) inhibitors in biological functions are
frequently investigated in animal models. However, there is little data on their analgesic …

Epidural injection of cyclooxygenase-2 inhibitors has been suggested as a useful
therapeutic modality in pain management in animal studies and clinical settings. Direct …

Purpose: To examine the effect of a cyclooxygenase (COX)-2 inhibitor on the maintenance
of mechanical allodynia induced by skin incision (an animal model of postoperative incident …

Background Prostaglandins play a major role in inflammation and pain. They are
synthesized by the two cyclooxygenase (COX) isoforms: COX-1, which is expressed …

Background Pre‐emptive analgesia in perioperative care has potential benefits for patients.
The pre‐emptive and postoperative analgesic effects of the cyclooxygenase‐2 inhibitor …