Bone structure and formation: A new perspective
Bone is a hierarchically structured composite material which, in addition to its obvious
biological value, has been well studied by the materials engineering community because of …
biological value, has been well studied by the materials engineering community because of …
Scanning electron microscopic analysis of the mineralization of type I collagen via a polymer-induced liquid-precursor (PILP) process
We have put forth the hypothesis that collagen is mineralized during bone formation by
means of a polymer-induced liquid-precursor (PILP) process, in which a liquid-phase …
means of a polymer-induced liquid-precursor (PILP) process, in which a liquid-phase …
[HTML][HTML] Mimicking the nanostructure of bone: comparison of polymeric process-directing agents
TT Thula, F Svedlund, DE Rodriguez, J Podschun… - Polymers, 2010 - mdpi.com
The nanostructure of bone has been replicated using a polymer-induced liquid-precursor
(PILP) mineralization process. This polymer-mediated crystallization process yields …
(PILP) mineralization process. This polymer-mediated crystallization process yields …
Development of bone-like composites via the polymer-induced liquid-precursor (PILP) process. Part 1: influence of polymer molecular weight
Bone is an organic–inorganic composite consisting primarily of collagen fibrils and
hydroxyapatite crystals intricately interlocked to provide skeletal and metabolic functions …
hydroxyapatite crystals intricately interlocked to provide skeletal and metabolic functions …
In vitro mineralization of dense collagen substrates: a biomimetic approach toward the development of bone-graft materials
TT Thula, DE Rodriguez, MH Lee, L Pendi, J Podschun… - Acta biomaterialia, 2011 - Elsevier
Bone is an organic–inorganic composite which has hierarchical structuring that leads to high
strength and toughness. The nanostructure of bone consists of nanocrystals of …
strength and toughness. The nanostructure of bone consists of nanocrystals of …
Molecular mechanisms for intrafibrillar collagen mineralization in skeletal tissues
The critical role of the self-assembled structure of collagen in skeletal mineralization is long
recognized, yet the angstrom to tens of nanometers length-scale nucleation mechanism of …
recognized, yet the angstrom to tens of nanometers length-scale nucleation mechanism of …
Protein-free formation of bone-like apatite: New insights into the key role of carbonation
The nanometer-sized plate-like morphology of bone mineral is necessary for proper bone
mechanics and physiology. However, mechanisms regulating the morphology of these …
mechanics and physiology. However, mechanisms regulating the morphology of these …
Hierarchical structures of bone and bioinspired bone tissue engineering
Bone, as a mineralized composite of inorganic (mostly carbonated hydroxyapatite) and
organic (mainly type I collagen) phases, possesses a unique combination of remarkable …
organic (mainly type I collagen) phases, possesses a unique combination of remarkable …
Spherulitic crystal growth drives mineral deposition patterns in collagen‐based materials
E Macías‐Sánchez, NV Tarakina… - Advanced Functional …, 2022 - Wiley Online Library
The formation of the hard tissues that provide support and mobility to organisms is achieved
through the interplay of inorganic crystals and an organic framework composed of collagen …
through the interplay of inorganic crystals and an organic framework composed of collagen …
Journey of mineral precursors in bone mineralization: Evolution and inspiration for biomimetic design
Y Zhang, S Ma, J Nie, Z Liu, F Chen, A Li, D Pei - Small, 2024 - Wiley Online Library
Bone mineralization is a ubiquitous process among vertebrates that involves a dynamic
physical/chemical interplay between the organic and inorganic components of bone tissues …
physical/chemical interplay between the organic and inorganic components of bone tissues …