Arsenic-induced epigenetic changes in cancer development
WN Saintilnord, Y Fondufe-Mittendorf - Seminars in cancer biology, 2021 - Elsevier
Arsenic is a ubiquitous metalloid whose high levels of toxicity pose major health concerns to
millions of people worldwide by increasing susceptibility to various cancers and non-cancer …
millions of people worldwide by increasing susceptibility to various cancers and non-cancer …
Epigenetic dysregulations in arsenic-induced carcinogenesis
Simple Summary Arsenic is a chemical element that is toxic, and long-term exposure to it
causes cancers such as lung, skin, liver, and bladder cancers. Over 150 million people …
causes cancers such as lung, skin, liver, and bladder cancers. Over 150 million people …
Epigenomic reprogramming in inorganic arsenic-mediated gene expression patterns during carcinogenesis
M Eckstein, R Eleazer, M Rea… - Reviews on …, 2017 - degruyter.com
Arsenic is a ubiquitous metalloid that is not mutagenic but is carcinogenic. The mechanism
(s) by which arsenic causes cancer remain unknown. To date, several mechanisms have …
(s) by which arsenic causes cancer remain unknown. To date, several mechanisms have …
[HTML][HTML] Oncogenomic disruptions in arsenic-induced carcinogenesis
Chronic exposure to arsenic affects more than 200 million people worldwide, and has been
associated with many adverse health effects, including cancer in several organs. There is …
associated with many adverse health effects, including cancer in several organs. There is …
Molecular mechanisms of arsenic carcinogenesis
C Huang, Q Ke, M Costa, X Shi - Molecular and cellular biochemistry, 2004 - Springer
Arsenic is a metalloid compound that is widely distributed in the environment. Human
exposure of this compound has been associated with increased cancer incidence. Although …
exposure of this compound has been associated with increased cancer incidence. Although …
Epigenetic targets of arsenic: emphasis on epigenetic modifications during carcinogenesis
ABSTRACT DNA methylation and histone modification promote opening and closure of
chromatin structure, which affects gene expression without altering the DNA sequence …
chromatin structure, which affects gene expression without altering the DNA sequence …
Oxidative stress, epigenetics, and cancer stem cells in arsenic carcinogenesis and prevention
L Li, F Chen - Current pharmacology reports, 2016 - Springer
The carcinogenic role of arsenic has been extensively studied for more than half century.
How arsenic causes human cancer, however, remains to be fully elucidated. In this brief …
How arsenic causes human cancer, however, remains to be fully elucidated. In this brief …
Arsenic-mediated cellular signal transduction, transcription factor activation, and aberrant gene expression: implications in carcinogenesis
C Yang, K Frenkel - Journal of environmental pathology …, 2002 - dl.begellhouse.com
Arsenic is a common environmental and occupational pollutant and a wellknown human
carcinogen that causes cancers in many human organs. The exact molecular mechanisms …
carcinogen that causes cancers in many human organs. The exact molecular mechanisms …
Arsenic and cancer: Evidence and mechanisms
Arsenic is a potent carcinogen and poses a significant health concern worldwide. Exposure
occurs through ingestion of drinking water and contaminated foods and through inhalation …
occurs through ingestion of drinking water and contaminated foods and through inhalation …
Effects of arsenic exposure on DNA methylation and epigenetic gene regulation
JF Reichard, A Puga - Epigenomics, 2010 - Taylor & Francis
Arsenic is a nonmutagenic human carcinogen that induces tumors through unknown
mechanisms. A growing body of evidence suggests that its carcinogenicity results from …
mechanisms. A growing body of evidence suggests that its carcinogenicity results from …