Liver fibrosis represents a health problem with significant morbidity and mortality that affects
100 million people worldwide. It is a final pathway to several chronic liver diseases and is …

Oxidative stress is a reflection of the imbalance between the production of reactive oxygen
species (ROS) and the scavenging capacity of the antioxidant system. Excessive ROS …

The pathogenesis of hepatic fibrosis involves significant deposition of fibrilar collagen and
other extracellular matrix proteins. It is a rather dynamic process of wound healing in …

Liver fibrosis can be considered as a dynamic and highly integrated cellular response to
chronic liver injury [1]. Whatever the etiology, the evolution of chronic liver disease (CLD) is …

Liver fibrosis is the pathological process of excessive extracellular matrix deposition after
liver injury and is a precursor to cirrhosis, hepatocellular carcinoma (HCC). It is essentially a …

The liver is a critical system for metabolism in human beings, which plays an essential role
in an abundance of physiological processes and is vulnerable to endogenous or exogenous …

Hepatic fibrosis is a dynamic process that occurs as a wound healing response against liver
injury. During fibrosis, crosstalk between parenchymal and non-parenchymal cells …

Hepatic fibrogenesis is a pathophysiological outcome of chronic liver injury hallmarked by
excessive accumulation of extracellular matrix proteins. Fibrosis is a dynamic process that …

The liver is a central organ in the human body, coordinating several key metabolic roles. The
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …

Liver fibrosis is a clinically significant finding that has major impacts on patient morbidity and
mortality. The mechanism of fibrosis involves many different cellular pathways, but the major …