Abstract SARS-CoV-2 main protease (Mpro) is a well-recognized target for COVID-19
therapy. Green tea (−)-epigallocatechin-3-gallate (EGCG) possesses Mpro-inhibitory activity; …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for
coronavirus disease 2019 (COVID-19), encodes two proteases required for replication. The …

COVID-19 pandemic results in record high deaths in many countries. Although a vaccine for
SARS-CoV-2 is now available, effective antiviral drugs to treat coronavirus diseases are not …

COVID‐19, a global pandemic, has caused over 750,000 deaths worldwide as of August
2020. A vaccine or remedy for SARS‐CoV‐2, the virus responsible for COVID‐19, is …

SARS-CoV-2 main protease is a possible target for protection against viral infection. This
study examined the inhibitory effect of food phytochemicals on the main protease of SARS …

Abstract SARS-CoV-2 main protease (M pro) cleaves the viral polypeptide 1a and 1ab in a
site-specific ((LQ|(S, A, G)) manner and produce functional enzymes for mediating viral …

Because of the emerging variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in different regions of the world, the battle with infectious coronavirus disease …

Targeted covalent inhibition represents one possible strategy to block the function of SARS-
CoV-2 Main Protease (MPRO), an enzyme that plays a critical role in the replication of the …

Owing to the instability of Epigallocatechin Gallate (EGCG), it may undergo auto-oxidation
and form oxidised products or dimers. In the present study, we aimed to evaluate the …

The main protease (Mpro) of SARS-CoV-2 is a essential enzyme that facilitates viral
transcription and replication. Furthermore, the conservation of Mpro across different variants …