Functional alteration patterns of default mode networks: comparisons of normal aging, amnestic mild cognitive impairment and Alzheimer's disease

J Cha, HJ Jo, HJ Kim, SW Seo, HS Kim… - European Journal of …, 2013 - Wiley Online Library
Most default mode network (DMN) studies in patients with amnestic mild cognitive
impairment (aMCI) and Alzheimer's disease (AD) are based on the comparison of only two …

Inflection point in course of mild cognitive impairment: increased functional connectivity of default mode network

W Tao, X Li, J Zhang, Y Chen, C Ma… - Journal of …, 2017 - content.iospress.com
The alteration of the default mode network (DMN) functional connectivity (FC) has been
reported in patients with amnestic mild cognitive impairment (aMCI) as a predictor of …

Altered effective connectivity of the default mode network in resting-state amnestic type mild cognitive impairment

H Yan, Y Zhang, H Chen, Y Wang… - Journal of the International …, 2013 - cambridge.org
Amnestic mild cognitive impairment (aMCI) is the transitional, heterogeneous continuum
from normal elderly to Alzheimer's disease (AD). Previous studies have shown that brain …

Default mode network functional connectivity in early and late mild cognitive impairment: results from the Alzheimer's disease neuroimaging initiative

ES Lee, K Yoo, YB Lee, J Chung, JE Lim… - Alzheimer Disease & …, 2016 - journals.lww.com
Background: Default mode network (DMN) functional connectivity is one of the
neuroimaging candidate biomarkers of Alzheimer disease. However, no studies have …

Altered effective connectivity patterns of the default mode network in Alzheimer's disease: an fMRI study

Y Zhong, L Huang, S Cai, Y Zhang, KM von Deneen… - Neuroscience …, 2014 - Elsevier
The aim of this work is to investigate the differences of effective connectivity of the default
mode network (DMN) in Alzheimer's disease (AD) patients and normal controls (NC). The …

Altered default mode network connectivity in older adults with cognitive complaints and amnestic mild cognitive impairment

Y Wang, SL Risacher, JD West… - Journal of …, 2013 - journals.sagepub.com
Default mode network (DMN) disruption has been reported in Alzheimer's disease (AD), yet
the specific pattern of altered connectivity over the course of prodromal AD remains to be …

Differences and the relationship in default mode network intrinsic activity and functional connectivity in mild Alzheimer's disease and amnestic mild cognitive …

M Weiler, CVL Teixeira, MH Nogueira… - Brain …, 2014 - liebertpub.com
There is evidence that the default mode network (DMN) functional connectivity is impaired in
Alzheimer's disease (AD) and few studies also reported a decrease in DMN intrinsic activity …

Altered default mode network connectivity in Alzheimer's disease—a resting functional MRI and Bayesian network study

X Wu, R Li, AS Fleisher, EM Reiman… - Human brain …, 2011 - Wiley Online Library
A number of functional magnetic resonance imaging (fMRI) studies reported the existence of
default mode network (DMN) and its disruption due to the presence of a disease such as …

Age and hippocampal volume predict distinct parts of default mode network activity

M De Marco, S Ourselin, A Venneri - Scientific reports, 2019 - nature.com
Group comparison studies have established that activity in the posterior part of the default-
mode network (DMN) is down-regulated by both normal ageing and Alzheimer's disease …

Functional disintegration of the default mode network in prodromal Alzheimer's disease

KNH Dillen, HIL Jacobs, J Kukolja… - Journal of …, 2017 - content.iospress.com
Neurodegenerative brain changes can affect the functional connectivity strength between
nodes of the default-mode network (DMN), which may underlie changes in cognitive …