Update on head and neck cancer: current knowledge on epidemiology, risk factors, molecular features and novel therapies

F Pezzuto, L Buonaguro, F Caponigro, F Ionna… - Oncology, 2015 - karger.com
Tobacco use and alcohol consumption are the main risk factors associated with head and
neck squamous cell carcinoma (SCC) development due to their cytotoxic and mutagenic …

Head and neck cancer: Current challenges and future perspectives

GR Bhat, RG Hyole, J Li - Advances in Cancer Research, 2021 - Elsevier
Head and neck cancers are a heterogeneous, aggressive and genetically complex
collection of malignancies of the oral cavity, nasopharynx, oropharynx, hypopharynx, larynx …

Emerging drugs to treat squamous cell carcinomas of the head and neck

C Fung, JR Grandis - Expert opinion on emerging drugs, 2010 - Taylor & Francis
Importance of the field: Head and neck squamous cell carcinoma (HNSCC) is the eighth
leading cause of cancer death worldwide. Despite advances in surgery and chemoradiation …

Emerging drugs for head and neck cancer

Y Wen, JR Grandis - Expert opinion on emerging drugs, 2015 - Taylor & Francis
Introduction: Despite improvements in treatment, survival rates of head and neck squamous
cell carcinoma (HNSCC) are stagnant. The existing chemotherapeutic agents are non …

Recent advances in head and neck cancer

RI Haddad, DM Shin - New England Journal of Medicine, 2008 - Mass Medical Soc
There are more than half a million incident cases of squamous-cell carcinoma of the head
and neck worldwide each year, primarily affecting the oropharynx, oral cavity, hypopharynx …

[HTML][HTML] Basics of tumor development and importance of human papilloma virus (HPV) for head and neck cancer

C Wittekindt, S Wagner, CS Mayer… - GMS current topics in …, 2012 - ncbi.nlm.nih.gov
Abstract Head and Neck Squamous Cell Carcinomas (HNSCC) are the 6 th most common
cancers worldwide. While incidence rates for cancer of the hypopharynx and larynx are …

Applying the molecular biology and epigenetics of head and neck cancer in everyday clinical practice

CA Glazer, SS Chang, PK Ha, JA Califano - Oral oncology, 2009 - Elsevier
During the past decade, there has been a significant increase in knowledge regarding the
molecular biology and epigenetics of head and neck squamous cell carcinoma (HNSCC) …

Promising new molecular targeted therapies in head and neck cancer

K Dorsey, M Agulnik - Drugs, 2013 - Springer
Despite advances in multimodality therapies for the treatment of squamous cell carcinoma of
the head and neck (SCCHN), survival rates, functional outcomes and toxicities of therapy …

[HTML][HTML] Molecular landscape of head and neck cancer and implications for therapy

CS Farah - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinomas (HNSCC) arising from the oral cavity, pharynx,
and larynx constitute the 6 th most common human cancer. Human papillomavirus (HPV) …

[HTML][HTML] Current trends and future prospects of molecular targeted therapy in head and neck squamous cell carcinoma

N Kitamura, S Sento, Y Yoshizawa, E Sasabe… - International journal of …, 2020 - mdpi.com
In recent years, advances in drug therapy for head and neck squamous cell carcinoma
(HNSCC) have progressed rapidly. In addition to cytotoxic anti-cancer agents such as …