Suppression of lipolysis by acipimox is known to improve insulin-stimulated glucose
disposal, and this is an important phenomenon. The mechanism has been assumed to be …

Aims/hypothesis In the present study, we investigated the consequences of adipose tissue
lipolytic inhibition on skeletal muscle substrate use in type 2 diabetic patients. Materials and …

The increased risk of hypoglycemia during intensified treatment of type 1 diabetes mellitus
(T1DM) patients, who have a deficient glucagon secretory response, is largely attributed to …

1. Increased rates of fatty acid oxidation are frequently observed in patients with non-insulin-
dependent diabetes mellitus and may contribute to hyperglycaemia by both decreasing …

To determine whether insulin regulation of lipolysis is abnormal in subjects with poorly
controlled insulin-dependent diabetes mellitus (IDDM), free-fatty acid flux ([1-14C] palmitate) …

The aim of the study was to evaluate an acute decrease in NEFA levels during an oral
glucose tolerance test and its effects on glucose tolerance, muscle glucose uptake and …

We quantitated how lowering of free fatty acid (FFA) by an antilipolytic agent (acipimox) in
the fasting state changes glucose uptake in heart and skeletal muscles. Glucose uptake in …

The present study was performed in 17 nondiabetic subjects and was initiated to determine
whether enhanced adipose tissue lipolysis, either basal or catecholamine induced …

Effects of circulating insulin and glucose concentrations on skeletal muscle and adipose
tissue lipolytic activity were investigated in 10 type 1 diabetes patients with no endogenous …

We determined whether overnight inhibition of lipolysis by a long-acting nicotinic acid
derivative (acipimox) decreases gluconeogenesis from lactate in NIDDM patients. For this …