[HTML][HTML] Macrophage targeted theranostics as personalized nanomedicine strategies for inflammatory diseases

SK Patel, JM Janjic - Theranostics, 2015 - ncbi.nlm.nih.gov
Inflammatory disease management poses challenges due to the complexity of inflammation
and inherent patient variability, thereby necessitating patient-specific therapeutic …

Therapeutic applications of nanomedicine in autoimmune diseases: from immunosuppression to tolerance induction

M Gharagozloo, S Majewski, M Foldvari - … : Nanotechnology, Biology and …, 2015 - Elsevier
Autoimmune diseases are chronic, destructive diseases that can cause functional disability
and multiple organ failure. Despite significant advances in the range of therapeutic agents …

Nanomaterials to target immunity

R Manchanda, A Fernandez-Fernandez… - Advances in …, 2021 - Elsevier
Critical advances have recently been made in the field of immunotherapy, contributing to an
improved understanding of how to harness and balance the power of immune responses in …

Nanoengineered therapy aiming at the etiology of rheumatoid arthritis

R Li, Y Ma, J Hong, Y Ding - Nano Today, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovitis and
damage of cartilage and bone. Many efforts have been made in the past to develop …

Macrophage-targeted therapeutics for metabolic disease

KR Peterson, MA Cottam, AJ Kennedy… - Trends in pharmacological …, 2018 - cell.com
Macrophages are cells of the innate immune system that are resident in all tissues, including
metabolic organs such as the liver and adipose tissue (AT). Because of their phenotypic …

Macrophage‐mediated tumor cell phagocytosis: opportunity for nanomedicine intervention

X Zhou, X Liu, L Huang - Advanced functional materials, 2021 - Wiley Online Library
Macrophages are one of the most abundant non‐malignant cells in the tumor
microenvironment, playing critical roles in mediating tumor immunity. As important innate …

[HTML][HTML] Biomimetic nanoparticles for inflammation targeting

K Jin, Z Luo, B Zhang, Z Pang - Acta Pharmaceutica Sinica B, 2018 - Elsevier
There have been many recent exciting developments in biomimetic nanoparticles for
biomedical applications. Inflammation, a protective response involving immune cells, blood …

Regulation of synovial macrophages polarization by mimicking efferocytosis for therapy of osteoarthritis

H Yang, Z Yu, S Ji, J Yan, Y Kong… - Advanced Functional …, 2022 - Wiley Online Library
The progression of osteoarthritis is associated with chronic synovitis caused by synovial
macrophage infiltration and proinflammatory M1 polarization. Accordingly, repolarization of …

Hybrid biomimetic nanovesicles to drive high lung biodistribution and prevent cytokine storm for ARDS treatment

Q Qiao, X Liu, K Cui, X Li, T Tian, Y Yu, B Niu, L Kong… - ACS …, 2022 - ACS Publications
Acute respiratory distress syndrome (ARDS) has been a life threat for patients in ICUs. Vast
efforts have been devoted, while no medication has proved viable, which may be ascribed to …

Lymphoid organ-targeted nanomaterials for immunomodulation of cancer, inflammation, and beyond

JC Hsu, P Liu, Y Song, W Song, RJ Saladin… - Chemical Society …, 2024 - pubs.rsc.org
Nanomaterials exhibit significant potential for stimulating immune responses, offering both
local and systemic modulation across a variety of diseases. The lymphoid organs, such as …