Background The present study investigated whether single nucleotide polymorphisms
(SNPs) in the alpha-protein kinase 1 (ALPK1) gene are associated with gout in aboriginal …

Gout is of particularly high prevalence in the Māori and Pacific (Polynesian) populations of
Aotearoa New Zealand (NZ). Here, we investigated the contribution of common population …

Genetic variation in ABCG2 (rs2231142, Q141K), encoding a uric acid transporter, is
associated with gout in diverse populations. The aim of this study was to examine a role for …

Background Gout is a common arthritic disease resulting from elevated serum uric acid
(SUA) level. A large meta-analysis including 28,141 individuals identified nine single …

Current evidence suggests heredity and metabolic syndrome contributes to gout
progression. Specifically, the WDR1 and CLNK genes may play a role in gout progression in …

We have recently identified four novel genomic loci influencing gout susceptibility at the
genome-wide significance level (P< 5.0× 10–8) via genome-wide association study (GWAS) …

The relationship between the SLC2A9 (solute carrier family 2, member 9) gene
polymorphisms and gout was still inconsistent among the individual genetic association …

Objective The aim of this study was to examine whether serum urate-associated genetic
variants are associated with early-onset gout. Methods Participants with gout in the Genetics …

Introduction Two major gout-causing genes have been identified, the urate transport genes
SLC2A9 and ABCG2. Variation within the SLC17A1 locus, which encodes sodium …

Gout is one of the most common types of inflammatory arthritis, caused by the deposition of
monosodium urate crystals in and around the joints. Previous genome-wide association …