Polymorphism rs3733591 of the SLC2A9 gene and metabolic syndrome affect gout risk in Taiwan Biobank subjects

CN Lin, CC Ho, PC Hsieh, CH Hsiao, ON Nfor… - Frontiers in …, 2024 - frontiersin.org
Background: Over the past few decades, gout and diseases like metabolic syndrome (MetS)
have become more prevalent. Attempts have been made in Taiwan to identify the genes …

Association of gout polygenic risk score with age at disease onset and Tophaceous disease in European and Polynesian men with gout

NA Sumpter, R Takei, M Cadzow… - Arthritis & …, 2023 - Wiley Online Library
Objective To determine whether a gout polygenic risk score (PRS) is associated with age at
gout onset and tophaceous disease in European, East Polynesian, and West Polynesian …

The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets

H Rasheed, C McKinney, LK Stamp, N Dalbeth… - PloS one, 2016 - journals.plos.org
Deposition of crystallized monosodium urate (MSU) in joints as a result of hyperuricemia is a
central risk factor for gout. However other factors must exist that control the progression from …

Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity

MH Chuah, MP Leask, RK Topless, GD Gamble… - Arthritis Research & …, 2024 - Springer
Background Alcohol consumption is a risk factor for hyperuricaemia and gout. Multiple
single-nucleotide polymorphisms (SNPs) have been identified as associated with both …

The prevalence of the gout-associated polymorphism rs2231142 G>T in ABCG2 in a pregnant female Filipino cohort

Y Roman, M Tiirikainen, E Prom-Wormley - Clinical rheumatology, 2020 - Springer
Gout is a metabolic disorder and one of the most common arthritic conditions. Hyperuricemia
is the hallmark of developing gout and mostly caused by uric acid underexcretion. Gout …

The genetics of gout: towards personalised medicine?

N Dalbeth, LK Stamp, TR Merriman - BMC medicine, 2017 - Springer
Over the last decade, there have been major advances in the understanding of the genetic
basis of hyperuricaemia and gout as well as of the pharmacogenetics of urate-lowering …

Novel dysfunctional variant in ABCG2 as a cause of severe tophaceous gout: biochemical, molecular genetics and functional analysis

B Stiburkova, H Miyata, J Závada, M Tomčík… - …, 2016 - academic.oup.com
! The Author 2015. Published by Oxford University Press on behalf of the British Society for
Rheumatology. All rights reserved. For Permissions, please email: journals. permissions …

Polymorphisms of ABCG2 and SLC22A12 Genes Associated with Gout Risk in Vietnamese Population

N Thuy Duong, N Thy Ngoc, N Tran Minh Thang… - Medicina, 2019 - mdpi.com
Background and objective: Gout is a common form of inflammatory arthritis caused by the
crystallization of uric acid. Previous studies have demonstrated that the genetic …

Performance of gout definitions for genetic epidemiological studies: analysis of UK Biobank

M Cadzow, TR Merriman, N Dalbeth - Arthritis research & therapy, 2017 - Springer
Background Many different combinations of available data have been used to identify gout
cases in large genetic studies. The aim of this study was to determine the performance of …

[PDF][PDF] Associations between the SLC22A12 gene and gout susceptibility: a meta-analysis

Y Zou, J Du, Y Zhu, X Xie, J Chen… - Clin Exp Rheumatol, 2018 - clinexprheumatol.org
Associations between the SLC22A12 gene and gout susceptibility: a meta-analysis Page 1
Clinical and Experimental Rheumatology 2018 Clinical and Experimental Rheumatology 2018; …