Objectives To perform a genome-wide association study (GWAS) of gout cases versus
asymptomatic hyperuricaemia (AH) controls, and gout cases versus normouricaemia …

The aim of the present study was to investigate the association between genetic variants in
17 tagSNPs of the NLRP3 gene and the susceptibility to primary gouty arthritis. A genotype …

We conducted a case-control study to investigate the association between 3 common
NALP3 polymorphisms (rs10754558, rs7512998, and rs12137901) and the susceptibility to …

The effects of genetic variants on the interaction between hyperlipidemia and sex have not
been investigated among gout patients in Taiwan. Using Taiwan Biobank and the National …

In this study, we investigated the role of two single nucleotide polymorphisms in the
promoter region of the interleukin-8 gene (IL-8; rs4073 and rs2227306) in the susceptibility …

Gout is a common and very painful inflammatory arthritis caused by hyperuricaemia. This
Review provides an update on the genetics of hyperuricaemia and gout, including findings …

Objective Uric acid is the primary end product of purine metabolism. Increased serum uric
acid levels have been associated with gouty arthritis as well as with a variety of …

Objective. To validate the association between genetic polymorphisms and gout in
Japanese patients, and to investigate the cumulative effects of multiple genetic factors on the …

Gout is the most common inflammatory arthropathy and occurs in the setting of elevated
serum urate levels. Gout is also known to be associated with multiple comorbidities …

Gout is a common type of arthritis that is characterized by hyperuricemia, tophi, and joint
inflammation. Current evidence suggests that heredity contributes to the progression of gout …