Despite advances in pharmacologic and device treatment of chronic heart failure, long-term
morbidity and mortality remain high, and many patients progress to end-stage heart failure …

Heart transplantation has become a standard therapy option for advanced heart failure. The
translation of heart transplantation from innovative experiments to long-term clinical success …

Abstract Purpose of Review Despite the improvement in medical therapy for heart failure
and the advancements in mechanical circulatory support, heart transplantation (HT) still …

The first human heart transplantation was performed by Christian Barnard in 1967. While the
technical aspect had been worked out, allograft rejection was a major limitation in the early …

Despite advances in medical and device therapy, the prognosis and quality of life of patients
with advanced heart failure (HF) remains poor. For a carefully selected group of these …

Heart transplantation (HTx) has become standard treatment for selected patients with end-
stage heart failure. Improvements in immunosuppressant, donor procurement, surgical …

With the introduction of cyclosporin A in the early 1980s, heart transplantation was
transformed from an experimental procedure into a successful therapeutic option for patients …

Recent advances in the management of heart transplant recipients have resulted in
improved survival, particularly in the early post-transplant period. Although graft rejection …

The field of heart transplantation has seen significant progress in the past 40 years.
However, the breakthroughs in long-term outcome have seen stagnation in the past decade …

Heart transplantation keeps its leading position in the treatment of end-stage heart failure
(HF). Survival rates and functional status following heart transplantation are excellent …