Utility of the Zebrafish Model for Studying Neuronal and Behavioral Disturbances Induced by Embryonic Exposure to Alcohol, Nicotine, and Cannabis

AD Collier, AR Abdulai, SF Leibowitz - Cells, 2023 - mdpi.com
It is estimated that 5% of pregnant women consume drugs of abuse during pregnancy.
Clinical research suggests that intake of drugs during pregnancy, such as alcohol, nicotine …

Alcohol exposure during embryonic development: An opportunity to conduct systematic developmental time course analyses in zebrafish

A Facciol, B Tsang, R Gerlai - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Ethanol affects numerous neurobiological processes depending upon the developmental
stage at which it reaches the vertebrate embryo. Exposure time dependency may explain the …

Behavioral and gene regulatory responses to developmental drug exposures in zebrafish

AM Mech, M Merteroglu, IM Sealy, MT Teh… - Frontiers in …, 2022 - frontiersin.org
Developmental consequences of prenatal drug exposure have been reported in many
human cohorts and animal studies. The long-lasting impact on the offspring—including …

Acute and chronic alcohol effects in zebrafish

S Tran - Behavioral and Neural Genetics of Zebrafish, 2020 - Elsevier
Zebrafish have become a popular animal model for behavioral genetics and to study the
effects of alcohol on the brain. The reported effects acute (short-term) and chronic (long …

Ethanol effects on the developing zebrafish: neurobehavior and skeletal morphogenesis

MJ Carvan III, E Loucks, DN Weber… - Neurotoxicology and …, 2004 - Elsevier
Exposure to ethanol during development can lead to a constellation of congenital
anomalies, resulting in prenatal and postnatal failure to thrive, central nervous system (CNS) …

Long‐lasting implications of embryonic exposure to alcohol: Insights from zebrafish research

JH Cararo, EP Rico - Developmental Neurobiology, 2022 - Wiley Online Library
The harmful consumption of ethanol is associated with significant health problems and
social burdens. This drug activates a complex network of reward mechanisms and habit …

Developmental stage-dependent deficits induced by embryonic ethanol exposure in zebrafish: A neurochemical analysis

A Facciol, C Bailleul, S Nguyen, D Chatterjee… - Progress in Neuro …, 2020 - Elsevier
FASD results from the developing fetus being exposed to alcohol, and is characterized by
morphological, behavioural and cognitive deficits. However, the expression, severity and …

[HTML][HTML] Neurochemical and behavioral consequences of ethanol and/or caffeine exposure: Effects in zebrafish and rodents

CL Clayman, VP Connaughton - Current neuropharmacology, 2022 - ncbi.nlm.nih.gov
Zebrafish are increasingly being utilized to model the behavioral and neurochemical effects
of pharmaceuticals and, more recently, pharmaceutical interactions. Zebrafish models of …

Long-term behavioral alterations following embryonic alcohol exposure in three zebrafish populations

T Agues-Barbosa, AM de Souza, JN Gomes-de-Lima… - Neurotoxicology, 2023 - Elsevier
Fetal alcohol exposure may lead to a condition known as fetal alcohol spectrum disorder
(FASD), which comprises a set of consequences, including cognitive and behavioral …

Early embryonic ethanol exposure impairs shoaling and the dopaminergic and serotoninergic systems in adult zebrafish

C Buske, R Gerlai - Neurotoxicology and teratology, 2011 - Elsevier
Fetal alcohol syndrome (FAS) is a devastating disorder accompanied by numerous
morphological and behavioral abnormalities. Human FAS has been modeled in laboratory …