The inflammatory response in myocardial infarction
NG Frangogiannis, CW Smith… - Cardiovascular …, 2002 - academic.oup.com
One of the major therapeutic goals of modern cardiology is to design strategies aimed at
minimizing myocardial necrosis and optimizing cardiac repair following myocardial …
minimizing myocardial necrosis and optimizing cardiac repair following myocardial …
Monocytes, macrophages, and metabolic disease in atherosclerosis
Atherosclerotic cardiovascular disease (CVD) is a lipid-driven chronic inflammatory disease,
in which macrophages are responsible for taking up these lipids and driving disease …
in which macrophages are responsible for taking up these lipids and driving disease …
[PDF][PDF] Cardiac macrophages and emerging roles for their metabolism after myocardial infarction
EB Thorp - Journal of Clinical Investigation, 2023 - Am Soc Clin Investig
Interest in cardioimmunology has reached new heights as the experimental cardiology field
works to tap the unrealized potential of immunotherapy for clinical care. Within this space is …
works to tap the unrealized potential of immunotherapy for clinical care. Within this space is …
Targeting macrophages using nanoparticles: a potential therapeutic strategy for atherosclerosis
X Zang, M Cheng, X Zhang, X Chen - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Atherosclerosis is one of the leading causes of vascular diseases, with high morbidity and
mortality worldwide. Macrophages play a critical role in the development and local …
mortality worldwide. Macrophages play a critical role in the development and local …
New insights into the immunobiology of mononuclear phagocytic cells and their relevance to the pathogenesis of cardiovascular diseases
Macrophages are the primary immune cells that reside within the myocardium, suggesting
that these mononuclear phagocytes are essential in the orchestration of cardiac immunity …
that these mononuclear phagocytes are essential in the orchestration of cardiac immunity …
Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte …
M Tokutome, T Matoba, Y Nakano… - Cardiovascular …, 2019 - academic.oup.com
Aims Monocyte-mediated inflammation is a major mechanism underlying myocardial
ischaemia–reperfusion (IR) injury and the healing process after acute myocardial infarction …
ischaemia–reperfusion (IR) injury and the healing process after acute myocardial infarction …
Bridging innate immunity and myocardial ischemia/reperfusion injury: the search for therapeutic targets
F Arslan, DPV de Kleijn, L Timmers… - Current …, 2008 - ingentaconnect.com
Myocardial infarction necessitates new therapeutic interventions, since it still results in high
morbidity and mortality worldwide. Reperfusion therapy itself results in (acceleration of) …
morbidity and mortality worldwide. Reperfusion therapy itself results in (acceleration of) …
Macrophages and immune cells in atherosclerosis: recent advances and novel concepts
C Cochain, A Zernecke - Basic research in cardiology, 2015 - Springer
Atherosclerotic lesion-related thrombosis is the major cause of myocardial infarction and
stroke, which together constitute the leading cause of mortality worldwide. The inflammatory …
stroke, which together constitute the leading cause of mortality worldwide. The inflammatory …
The immune system and cardiac repair
NG Frangogiannis - Pharmacological research, 2008 - Elsevier
Myocardial infarction is the most common cause of cardiac injury and results in acute loss of
a large number of myocardial cells. Because the heart has negligible regenerative capacity …
a large number of myocardial cells. Because the heart has negligible regenerative capacity …
Macrophages: promising targets for the treatment of atherosclerosis
HM Wilson, RN Barker, LP Erwig - Current vascular …, 2009 - ingentaconnect.com
Atherosclerosis is now recognised as a chronic inflammatory disease occurring within the
artery wall and ultimately responsible for myocardial infarction, stroke and peripheral …
artery wall and ultimately responsible for myocardial infarction, stroke and peripheral …