The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood

P Lichtenstein, E Carlström, M Råstam… - American Journal of …, 2010 - Am Psychiatric Assoc
Objective: Autism spectrum disorders are considered to be among the most heritable mental
disorders, a notion based on surprisingly sparse data from small clinical studies. Population …

Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study

S Lundström, A Reichenberg, J Melke… - Journal of Child …, 2015 - Wiley Online Library
Background Evidence from twin and molecular genetic studies is accumulating that Autism
Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is …

Genetic heterogeneity between the three components of the autism spectrum: a twin study

A Ronald, F Happé, P Bolton, LM Butcher… - Journal of the American …, 2006 - Elsevier
OBJECTIVE: This study investigated the etiology of autistic-like traits in the general
population and the etiological overlap between the three aspects of the triad of impairments …

A Danish population-based twin study on autism spectrum disorders

C Nordenbæk, M Jørgensen, KO Kyvik… - European child & …, 2014 - Springer
Genetic epidemiological studies of Autism Spectrum Disorders (ASDs) based on twin pairs
ascertained from the population and thoroughly assessed to obtain a high degree of …

The genetics of autism

SJ Spence - Seminars in pediatric neurology, 2004 - Elsevier
Autism spectrum disorders (ASD) are among the most heritable of all neuropsychiatric
disorders. Discovery of autism susceptibility genes has been the focus of intense research …

Different neurodevelopmental symptoms have a common genetic etiology

E Pettersson, H Anckarsäter, C Gillberg… - Journal of Child …, 2013 - Wiley Online Library
Background Although neurodevelopmental disorders are demarcated as discrete entities in
the Diagnostic Statistical Manual of mental disorders, empirical evidence indicates that there …

Genetic influences in childhood-onset psychiatric disorders: autism and attention-deficit/hyperactivity disorder

SL Smalley - The American Journal of Human Genetics, 1997 - Elsevier
Unlike such psychiatric disorders as depression, schizo- symptoms such as aggression,
anxiety, and obsessivecompulsive behaviors but little or no inprovement in phrenia, and …

Autism spectrum disorders and autistic traits: a decade of new twin studies

A Ronald, RA Hoekstra - … Journal of Medical Genetics Part B …, 2011 - Wiley Online Library
Researchers continue to pursue a better understanding of the symptoms, comorbidities, and
causes of autism spectrum disorders. In this article we review more than 30 twin studies of …

A twin study of autism symptoms in Sweden

A Ronald, H Larsson, H Anckarsäter… - Molecular …, 2011 - nature.com
This study aimed to identify empirically the number of factors underlying autism symptoms—
social impairments, communication impairments, and restricted repetitive behaviors and …

Heritability of autism spectrum disorders: a meta‐analysis of twin studies

B Tick, P Bolton, F Happé, M Rutter… - Journal of Child …, 2016 - Wiley Online Library
Background The etiology of Autism Spectrum Disorder (ASD) has been recently debated
due to emerging findings on the importance of shared environmental influences. However …