Differential effects of CXCR4‐CXCL12‐ and CXCR7‐CXCL12‐mediated immune reactions on murine P0106–125‐induced experimental autoimmune neuritis

A Brunn, O Utermöhlen, M Mihelcic… - Neuropathology and …, 2013 - Wiley Online Library
Aim The role of chemokines and their receptors, which regulate trafficking and homing of
leucocytes to inflamed organs in human or murine autoimmune neuritis, has not yet been …

Antagonism of the chemokine receptors CXCR3 and CXCR4 reduces the pathology of experimental autoimmune encephalomyelitis

RE Kohler, I Comerford, S Townley… - Brain …, 2008 - Wiley Online Library
Chemokines regulate lymphocyte trafficking under physiologic and pathologic conditions. In
this study, we have investigated the role of CXCR3 and CXCR4 in the activation of T …

CXC chemokine receptors expression during chronic relapsing experimental autoimmune encephalomyelitis

AR Glabinski, S O'BRYANT, K Selmaj… - Annals of the New …, 2000 - Wiley Online Library
Chemokines are small proinflammatory cytokines that possess the ability to stimulate
migration of inflammatory cells towards the tissue site of inflammation. Previous reports …

The chemokine receptor antagonist, TAK‐779, decreased experimental autoimmune encephalomyelitis by reducing inflammatory cell migration into the central …

J Ni, YN Zhu, XG Zhong, Y Ding, LF Hou… - British journal of …, 2009 - Wiley Online Library
Background and purpose: The C–C chemokine receptor CCR5, and the C–X–C chemokine
receptor CXCR3 are involved in the regulation of T cell‐mediated immune responses, and in …

CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis

LV Bagaeva, P Rao, JM Powers… - The Journal of …, 2006 - journals.aai.org
Experimental autoimmune encephalomyelitis (EAE) is a Tcell-mediated autoimmune
disease of the CNS that is widely used as an animal model of multiple sclerosis. In this …

Lymphoid chemokines in the diagnosis, monitoring and treatment of inflammatory disease

BM Segal, L Bagaeva - US Patent 7,390,884, 2008 - Google Patents
Experimental autoimmune encephalomyelitis (EAE) is a Th1-mediated autoimmune disease
of the central nervous system that is widely used as an animal model of multiple sclerosis …

Lymphoid chemokines in the diagnosis, monitoring and treatment of inflammatory disease

BM Segal, L Bagaeva - US Patent 8,546,538, 2013 - Google Patents
Experimental autoimmune encephalomyelitis (EAE) is a Th1-mediated autoimmune disease
of the central nervous system that is widely used as an animal model of multiple sclerosis …

The role of CXCL1/CXCR2 axis in neurological diseases

S Jiang, J Liang, W Li, L Wang, M Song, S Xu… - International …, 2023 - Elsevier
The CXC chemokine ligand (CXCL) 1 and its receptor CXC chemokine receptor (CXCR) 2
are widely expressed in the peripheral nervous systems (PNS) and central nervous systems …

Nitric oxide inhibits CXCL12 expression in neuroinflammation

F Petković, J Blaževski, M Momčilović… - Immunology and cell …, 2013 - Wiley Online Library
Chemokine CXCL12 (C‐X‐C motif chemokine ligand 12) restricts immune cell invasion of
the central nervous system (CNS) and limits neuroinflammation in experimental autoimmune …

Severe disease, unaltered leukocyte migration, and reduced IFN-γ production in CXCR3−/− mice with experimental autoimmune encephalomyelitis

LP Liu, DR Huang, M Matsui, TT He, T Hu… - The Journal of …, 2006 - journals.aai.org
Experimental autoimmune encephalomyelitis (EAE) is a CD4+ Th1 T cell-mediated disease
of the CNS, used to study certain aspects of multiple sclerosis. CXCR3, the receptor for …