Chemokine receptor CXCR3: an unexpected enigma
L Liu, MK Callahan, DR Huang… - Current topics in …, 2005 - Elsevier
CXCR3, the receptor for CXCL9/MIG, CXCL10/IP‐10, and CXCL11/I‐TAC, is preferentially
expressed on activated Th1 T cells and has been predicted to play an important role in their …
expressed on activated Th1 T cells and has been predicted to play an important role in their …
Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced …
S Eltayeb, AL Berg, H Lassmann, E Wallström… - Journal of …, 2007 - Springer
Background The CC chemokine receptors CCR1, CCR2 and CCR5 are critical for the
recruitment of mononuclear phagocytes to the central nervous system (CNS) in multiple …
recruitment of mononuclear phagocytes to the central nervous system (CNS) in multiple …
CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis
Y Zohar, G Wildbaum, R Novak… - The Journal of …, 2018 - Am Soc Clin Investig
A single G protein–coupled receptor (GPCR) can activate multiple signaling cascades
based on the binding of different ligands. The biological relevance of this feature in immune …
based on the binding of different ligands. The biological relevance of this feature in immune …
CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis
Y Zohar, G Wildbaum, R Novak… - The Journal of …, 2017 - Am Soc Clin Investig
A single G protein–coupled receptor (GPCR) can activate multiple signaling cascades
based on the binding of different ligands. The biological relevance of this feature in immune …
based on the binding of different ligands. The biological relevance of this feature in immune …
CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis
Y Zohar, G Wildbaum, R Novak… - The Journal of …, 2014 - Am Soc Clin Investig
A single G protein–coupled receptor (GPCR) can activate multiple signaling cascades
based on the binding of different ligands. The biological relevance of this feature in immune …
based on the binding of different ligands. The biological relevance of this feature in immune …
Pattern of CXCR7 gene expression in mouse brain under normal and inflammatory conditions
The chemokine stromal cell-derived factor-1 (SDF-1)/CXCL12 acting via its G-protein
coupled receptor (GPCR) CXCR4 has been implicated in neurogenesis, neuromodulation …
coupled receptor (GPCR) CXCR4 has been implicated in neurogenesis, neuromodulation …
[HTML][HTML] Expression of rat I-TAC/CXCL11/SCYA11 during central nervous system inflammation: comparison with other CXCR3 ligands
SR McColl, S Mahalingam, M Staykova… - Laboratory …, 2004 - Elsevier
The chemokines are a large gene superfamily with critical roles in development and
immunity. The chemokine receptor CXCR3 appears to play a major role in the trafficking of …
immunity. The chemokine receptor CXCR3 appears to play a major role in the trafficking of …
CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation
F Wu, Y Zhao, T Jiao, D Shi, X Zhu, M Zhang… - Journal of …, 2015 - Springer
Background Chemokines and chemokine receptors cooperate to promote immune cell
recruitment to the central nervous system (CNS). In this study, we investigated the roles of …
recruitment to the central nervous system (CNS). In this study, we investigated the roles of …
Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment
M Krumbholz, D Theil, S Cepok, B Hemmer, P Kivisäkk… - Brain, 2006 - academic.oup.com
Understanding the mechanisms of immune cell migration to multiple sclerosis lesions offers
significant therapeutic potential. This study focused on the chemokines CXCL12 (SDF-1) …
significant therapeutic potential. This study focused on the chemokines CXCL12 (SDF-1) …
Opposing effects of CXCR3 and CCR5 deficiency on CD8+ T cell-mediated inflammation in the central nervous system of virus-infected mice
C De Lemos, JE Christensen, A Nansen… - The Journal of …, 2005 - journals.aai.org
T cells play a key role in the control of viral infection in the CNS but may also contribute to
immune-mediated cell damage. To study the redundancy of the chemokine receptors …
immune-mediated cell damage. To study the redundancy of the chemokine receptors …